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AG208

VGT 1 Peptide

control for AB5905, liquid

Synonym(s):

VGLUT1, BNPI

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.42
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Product Name

Vesicular Glutamate Transporter 1, control peptide for AB5905,

biological source

rat

Quality Segment

100

form

liquid

manufacturer/tradename

Chemicon®

concentration

1 mg/mL

technique(s)

cell based assay: suitable

NCBI accession no.

NP_446311

UniProt accession no.

Q62634

shipped in

dry ice

General description

Synthetic peptide from rat VGLUT1 protein.
VGLUT1 is expressed in a subset of glutamate neurons and transports glutamate into native synaptic vesicles from the brain, exhibiting a conductance for chloride that is blocked by glutamate. Vesicular glutamate transport has a substantially lower apparent affinity than the plasma membrane excitatory amino acid transporters. Glutamate transport by VGLUT1 is saturated with a K(m) of approximately 2 mM, in the same range as transport by synaptic vesicles. Finally, plasma membrane glutamate transporters recognize both aspartate and glutamate as substrates, whereas VGLUT1 does not recognize aspartate.

Application

For use in blocking the reactivity of AB5905.

Optimal working dilution must be determined by the end user.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

12 - Non Combustible Liquids

wgk

nwg

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