Millipore Sigma Vibrant Logo

579002 Tamoxifen, 4-Hydroxy-, (Z)- - CAS 68047-06-3 - Calbiochem

Tamoxifen, 4-Hydroxy-, (Z), CAS 68047-06-3, is a cell-permeable, active metabolite of Tamoxifen that is more potent than the parent compound and inhibits PKC by modifying its catalytic domain.

Tamoxifen, 4-Hydroxy-, (Z)- - CAS 68047-06-3 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (Z)-4-Hydroxytamoxifen, 4-OH-TAM, Estrogen Receptor Signaling Regulator II

Primary Target: PKC
View Products on Sigmaaldrich.com
579002
  
Price could not be retrieved
Minimum Quantity is a multiple of
Maximum Quantity is
Upon Order Completion More Information
You Saved ()
 
—
Request Pricing
—
Limited Availability Limited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

       

      Contact Customer Service

      Overview

      Key Spec Table

      CAS #Empirical Formula
      68047-06-3C₂₆H₂₉NO₂
      Description
      OverviewA cell-permeable, active metabolite of Tamoxifen (Cat. No. 579000) that acts as a potent inhibitor of PKC. It is more potent than the parent compound and inhibits PKC by modifying its catalytic domain. Also available as a 10 mM solution in EtOH (Cat. No. 508225).
      Catalogue Number579002
      Brand Family Calbiochem®
      Synonyms(Z)-4-Hydroxytamoxifen, 4-OH-TAM, Estrogen Receptor Signaling Regulator II
      References
      ReferencesGundimeda, U., et al. 1996. J. Biol. Chem. 271, 13504.
      Ye, Q. and Bodell, W.J. 1996. Carcinogenesis 17, 1747.
      Laser, R., et al. 1985. Eur. J. Cancer Clin. Oncol. 21, 985.
      Jordan, V.C., et al. 1978. J. Toxicol. Environ. Health 4, 364.
      Product Information
      CAS number68047-06-3
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₂₆H₂₉NO₂
      Chemical formulaC₂₆H₂₉NO₂
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ200
      Applications
      ApplicationTamoxifen, 4-Hydroxy-, (Z), CAS 68047-06-3, is a cell-permeable, active metabolite of Tamoxifen that is more potent than the parent compound and inhibits PKC by modifying its catalytic domain.
      Biological Information
      Primary TargetPKC
      Purity≥99% by HPLC
      Physicochemical Information
      Cell permeableY
      Safety Information according to GHS
      RTECSSL1210000
      Safety Information
      R PhraseR: 22-45-60-61-64

      Harmful if swallowed.
      May cause cancer.
      May impair fertility.
      May cause harm to the unborn child.
      May cause harm to breastfed babies.
      S PhraseS: 36/37/39-45

      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful & Carcinogenic / Teratogenic
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Global Trade Item Number
      Catalogue Number GTIN
      579002 0