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559387 SB 202474 - CAS 172747-50-1 - Calbiochem

SB 202474 - CAS 172747-50-1 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 4-Ethyl-2(p-methoxyphenyl)-5-(4ʹ-pyridyl)-IH-imidazole

Primary Target: p38β
559387
  
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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      172747-50-1C₁₇H₁₇N₃O
      Description
      Overview

      This product has been discontinued.



      A negative control for SB202190 (Cat. No. 559388) and SB203580 (Cat. No. 559389) in p38 MAP kinase inhibition studies.
      Catalogue Number559387
      Brand Family Calbiochem®
      Synonyms4-Ethyl-2(p-methoxyphenyl)-5-(4ʹ-pyridyl)-IH-imidazole
      References
      ReferencesNath, R., et al. 2001. Cell Mol. Biol. Lett. 6, 173.
      Yu, R., et al. 2000. J. Biol. Chem. 275, 2322.
      Lee, J.C., et al. 1994. Nature 372, 739.
      Product Information
      CAS number172747-50-1
      ATP CompetitiveN
      FormOff-white solid
      Hill FormulaC₁₇H₁₇N₃O
      Chemical formulaC₁₇H₁₇N₃O
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetp38β
      Primary Target IC<sub>50</sub>34 nM
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      559387 0

      Documentation

      SB 202474 - CAS 172747-50-1 - Calbiochem MSDS

      Title

      Safety Data Sheet (SDS) 

      SB 202474 - CAS 172747-50-1 - Calbiochem Certificates of Analysis

      TitleLot Number
      559387

      References

      Reference overview
      Nath, R., et al. 2001. Cell Mol. Biol. Lett. 6, 173.
      Yu, R., et al. 2000. J. Biol. Chem. 275, 2322.
      Lee, J.C., et al. 1994. Nature 372, 739.

      Citations

      Title
    • Ralf Gutzmer, et al. (2005) Histamine H4 receptor stimulation suppresses IL-12p70 production and mediates chemotaxis in human monocyte-derived dendritic cells. Journal of Immunology 5224-5232.
      		•
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision19-April-2011 RFH
      Synonyms4-Ethyl-2(p-methoxyphenyl)-5-(4ʹ-pyridyl)-IH-imidazole
      DescriptionA negative control for MAP kinase inhibition studies.
      FormOff-white solid
      CAS number172747-50-1
      Chemical formulaC₁₇H₁₇N₃O
      Structure formulaStructure formula
      Purity≥97% by HPLC
      SolubilityDMSO (25 mg/ml) or methanol
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesNath, R., et al. 2001. Cell Mol. Biol. Lett. 6, 173.
      Yu, R., et al. 2000. J. Biol. Chem. 275, 2322.
      Lee, J.C., et al. 1994. Nature 372, 739.
      Citation
    • Ralf Gutzmer, et al. (2005) Histamine H4 receptor stimulation suppresses IL-12p70 production and mediates chemotaxis in human monocyte-derived dendritic cells. Journal of Immunology 5224-5232.
      		•

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      Categories

      Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Protein Phosphorylation / Dephosphorylation > MAP Kinase Inhibitors