Millipore Sigma Vibrant Logo

851009 PyBOP

PyBOP Novabiochem®. CAS 128625-52-5, molar mass 520.39 g/mol.

PyBOP MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 128625-52-5 Molar Mass: 520.39 g/mol Hill Formula: C₁₈H₂₈N₆OP * F₆P
View Products on Sigmaaldrich.com
851009
View Pricing & Availability

Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
128625-52-5C₁₈H₂₈N₆OP * F₆P520.39 g/mol

Pricing & Availability

Catalogue Number AvailabilityPackaging Qty/Pack Price Quantity
8510090025
Retrieving availability...
—
Limited Availability Limited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      		 Plastic bottle 25 g
      Retrieving price...
      Price could not be retrieved
      Minimum Quantity is a multiple of
      Maximum Quantity is
      Upon Order Completion More Information
      You Saved ()
       
      —
      Request Pricing
      		 —
      8510090100
      Retrieving availability...
      —
      Limited Availability Limited Availability
      In Stock 
      Discontinued
      Limited Quantities Available
      Availability to be confirmed
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service
          Contact Customer Service

          		 Plastic bottle 100 g
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity is a multiple of
          Maximum Quantity is
          Upon Order Completion More Information
          You Saved ()
           
          —
          Request Pricing
          		 —
          Description
          Catalogue Number851009
          Replaces01-62-0016
          Brand Family Novabiochem®
          Alternate Names
          • Benzotriazole-1-yl-oxy-tris-pyrrolidino-phosphonium hexafluorophosphate
          Background InformationThe standard in situ coupling reagent for solid phase peptide synthesis [1-5]. This product can replace BOP in all applications without loss of performance. Unlike uronium-based reagents, PyBOP® does not give rise to guanidinated by-products during cyclization and fragment condensation reactions.

          The product number for this product was previously 01-62-0016.

          To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
          References
          Product Information
          CAS number128625-52-5
          Hill FormulaC₁₈H₂₈N₆OP * F₆P
          Molar Mass520.39 g/mol
          HS Code2933 99 80
          Structure formula ImageStructure formula Image
          Quality LevelMQ400
          Applications
          ApplicationPyBOP Novabiochem®. CAS 128625-52-5, molar mass 520.39 g/mol.
          Biological Information
          Physicochemical Information
          Density1.438 g/cm3 (20 °C)
          Melting Point140 - 155 °C
          Vapor pressure<1 hPa (25 °C)
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Hazard Pictogram(s) Hazard Pictogram(s)
          Hazard Pictogram(s)
          Hazard Statement(s)H302: Nociv în caz de înghiţire.
          H317: Poate provoca o reacţie alergică a pielii.
          H410: Foarte toxic pentru mediul acvatic cu efecte pe termen lung.
          Precautionary Statement(s)P261: Evitaţi să inspiraţi praful/ fumul/ gazul/ ceaţa/ vaporii/ spray-ul.
          P264: Spălaţi-vă pielea bine după utilizare.
          P273: Evitaţi dispersarea în mediu.
          P280: Purtaţi mănuşi de protecţie.
          P301 + P312: ÎN CAZ DE ÎNGHIȚIRE: Sunați la un CENTRU DE INFORMARE TOXICOLOGICĂ/un medic dacă nu vă simțiți bine.
          P302 + P352: ÎN CAZ DE CONTACT CU PIELEA: spălați cu multă apă.
          Signal WordAtenţie
          Storage class10 - 13 Alte lichide sau solide
          WGKWGK 3 puternică poluare a apei
          Safety Information
          Categories of dangeriritant
          Product Usage Statements
          Storage and Shipping Information
          StorageA se depozita între +2°C la +8°C.
          Packaging Information
          Transport Information
          Declaration (railroad and road) ADR, RIDUN 3077 , 9, III
          Declaration (transport by air) IATA-DGRUN 3077 , 9, III
          Declaration (transport by sea) IMDG-CodeUN 3077 , 9, III, Marine Pollutant: P
          Supplemental Information
          Specifications
          Color (visual)white to slight yellow to beige
          Appearance of substance (visual)powder
          Identity (IR)passes test
          Assay (HPLC, area%)≥ 99.0 % (a/a)
          Solubility (1 mmole in 2 ml DMF)clearly soluble
          Global Trade Item Number
          Catalogue Number GTIN
          8510090025 04027269081089
          8510090100 04027269081096

          Documentation

          PyBOP MSDS

          Title

          Safety Data Sheet (SDS) 

          PyBOP Certificates of Analysis

          Product Number PackagingSpecificationLot Number
          8510090025 Plastic bottlePDF Specification Document
          8510090100 Plastic bottlePDF Specification Document

          Brochure

          Title
          Novabiochem Coupling Reagent Flyer 2010
          Novabiochem Innovations 02/06
          Novabiochem Innovations 03/10
          Novabiochem Letters 01/14

          Citations

          Title
          • [1] J. Martinez, et al. (1985) J. Med. Chem., 28, 1874.
          • [2] J. Coste, et al. (1990) Tetrahedron Lett., 31, 205.
          • [3] G. B. Fields, et al. in 'Innovation & Perspectives in Solid Phase Synthesis, 1st International Symposium', R. Epton (Eds), SPCC UK Ltd., Birmingham, 1990, pp. 241.
          • [4] T. Høeg-Jensen, et al. (1991) Tetrahedron Lett., 32, 7617.
          • [5] R. von Eggelkraut-Gottanka, et al. (2003) Tetrahedron Lett., 44, 3551.