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14-738M Pim-3 Protein, active, 250 µg

14-738M
250 µg  Also available in 10 μg size (cat#14-738) and in bulk (cat# 14-738-K).
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      Overview

      Replacement Information
      Description
      Catalogue Number14-738M
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionPim-3 Protein, active, 250 µg
      OverviewN-terminal 6His-tagged, recombinant, human Pim-3
      References
      Product Information
      Quality LevelMQ100
      Applications
      ApplicationActive, N-terminal 6His-tagged, recombinant, human Pim-3, for use in Enzyme Assays.
      Key Applications
      • Enzyme Assays
      Biological Information
      Sourceexpressed by baculovirus in Sf21 cells
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
      Entrez Gene Number
      Entrez Gene SummaryPIM3 belongs to a family of protooncogenes that encode serine/threonine protein kinases (Mikkers et al., 2004 [PubMed 15199164]).[supplied by OMIM]
      Gene Symbol
      • PIM3
      • pim-3
      Protein TargetPim-3
      Purification MethodNi2+/NTA-agarose
      Target Sub-FamilyCAMK
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q86V86 # May be involved in cell cycle progression and anti- apoptosis process. Implicated in proliferation of human hepatoma cell lines.
      SIZE: 326 amino acids; 35863 Da
      TISSUE SPECIFICITY: Widely expressed. No expression in colon, thymus, and small intestine. Expressed in human hepatoma cell lines but not in normal liver tissues.
      SIMILARITY: SwissProt: Q86V86 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. & Contains 1 protein kinase domain.
      Molecular Weight39.6kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by phosphorylation of 250μM GGMEDIYFEFMGGKKK
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C from date of shipment
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 10 μg size (cat#14-738) and in bulk (cat# 14-738-K).
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      14-738M 04053252367311

      Related Products & Applications

      Alternative Packsize

      Catalogue Number Description  
      14-738 Pim-3 Protein, active, 10 µg Show Pricing & Availability

      Product Families

      Categories

      Life Science Research > Proteins and Enzymes > Purified Kinases
      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases