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14-698M PhKγ2 Protein, active, 250 µg

Active, GST-tagged, recombinant, PhKγ2, amino acids 1-301 containing the mutation F290L, for use in Kinase Assays.

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14-698M
250 µg  Also available in 10 μg size (cat#14-698) and in bulk (cat#14-698-K).
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      Overview

      Replacement Information
      Description
      Catalogue Number14-698M
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionPhKγ2 Protein, active, 250 µg
      OverviewGST-tagged, recombinant, PhKγ2, amino acids 1-301 containing the mutation F290L
      References
      Product Information
      Quality LevelMQ300
      Applications
      ApplicationActive, GST-tagged, recombinant, PhKγ2, amino acids 1-301 containing the mutation F290L, for use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      Sourceexpressed in E. coli
      Entrez Gene Number
      Gene Symbol
      • PHKG2
      • PSK-C3
      • PHK-gamma-T
      Protein TargetPhKg2
      Purification MethodGlutathione-agarose
      Target Sub-Familymisc
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P15735 # Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. This isozyme may regulate glycogeneolysis in the testis.
      SIZE: 406 amino acids; 46442 Da
      SUBUNIT: Polymer of 16 chains, four each of alpha, beta, gamma, and delta. Alpha and beta are regulatory chains, gamma is the catalytic chain, and delta is calmodulin.
      DISEASE: SwissProt: P15735 # Defects in PHKG2 are a cause of glycogen storage disease type 9C (GSD9C) [MIM:172471]; also known as autosomal liver glycogenosis. GSD9C is a metabolic disorder manifesting in infancy with hepatomegaly, growth retardation, and elevated plasma aminotransferases and lipids.
      SIMILARITY: SwissProt: P15735 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.
      Molecular Weight61.37kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by phosphorylation of ZIPtide (Catalog # 12-545)
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C from date of shipment
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 10 μg size (cat#14-698) and in bulk (cat#14-698-K).
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      14-698M 04053252925375

      Documentation