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528120 PIPER - CAS 213416-70-7 - Calbiochem

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528120
  
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      Overview

      Key Spec Table

      CAS #Empirical Formula
      213416-70-7C₃₈H₃₆N₄O₄
      Description
      Overview

      This product has been discontinued.



      A perylene-based ligand that potently inhibits human telomerase by binding to G-quadruplex DNA. The strongest binding site for PIPER appears to be the 3′-boundary of the G-quadruplex. Can also bind non-specifically to nucleic acids. May also be useful as an antiproliferative agent.

      Catalogue Number528120
      Brand Family Calbiochem®
      SynonymsN,Nʹ-bis[2-(1-Piperidino)ethyl]-3,4,9,10-perylenetetracarboxylic Diimide, Telomerase Inhibitor IV
      References
      ReferencesHan, H., et al. 1999. Biochemistry 38, 6981.
      Fedoroff, O.Y., et al. 1998. Biochemistry 37, 12367.
      Product Information
      CAS number213416-70-7
      ATP CompetitiveN
      FormDark purple solid
      Hill FormulaC₃₈H₃₆N₄O₄
      Chemical formulaC₃₈H₃₆N₄O₄
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary Targethuman telomerase
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Safety Information
      R PhraseR: 20/21/22-40-68

      Harmful by inhalation, in contact with skin and if swallowed.
      Limited evidence of a carcinogenic effect.
      Possible risks of irreversible effects.
      S PhraseS: 22-36

      Do not breathe dust.
      Wear suitable protective clothing.
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful & Carcinogenic / Teratogenic
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      528120 0