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101736 OSTEOMOLL® -

Solution for rapid decalcification (with fixation) for histology

OSTEOMOLL® - MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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101736
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      		 Plastic bottle 1 l
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      1017362500
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          		 Plastic bottle 2.5 l
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          Description
          Catalogue Number101736
          DescriptionOSTEOMOLL®
          OverviewOSTEOMOLL® - Solution for rapid decalcification (with fixation) for histology, is used for human cell diagnostics and serves to decalcify (demineralize) bone tissue (e. g. punched bone-marrow specimens) and other hard materials and to soften keratinized tissue of human origin, fixing the specimens in the same process.
          Decalcification is necessary for optical microscopic examinations of hard tissue in routine histological procedures. For the decalcification of sensitive, calcium-containing tissues, such as iliac crest biopsies, OSTEOSOFT® (Cat.no. 101728) can be used. Its formulation is based on EDTA. Its pendant, OSTEOMOLL®, can be used for the decalcification of hard tissue such as teeth and bone as its formulation is based on formaldehyde and hydrochloric acid. The amount of OSTEOMOLL®needed is dependent upon on the size, type and thickness of the material. A 30 ml portion of OSTEOMOLL®, which should completely cover the material, can be used twice if the solution is still clear and not contaminated.
          The material must first be cut to a thickness of max. 5 mm and an area of ​​6 cm2 (= max. Embedding cassette size). Both solutions are color-coded, to distinguish them from each other, fixatives and solvents used in the histological laboratory. OSTEOSOFT® is color-coded yellow, OSTEOMOLL® is color-coded blue. Whereby OSTEOSOFT® preserves the antigen structures in the tissue, thus, an IHC analysis can be performed, OSTEOMOLL® will be used for tissues that are not destined for antibody analysis.
          Both decalcifiers can be used for clinical diagnostic purposes and in laboratory accreditation processes as they are certified and registered as IVD and CE product. The quantity of OSTEOMOLL® required is dependent on the size, type, and density of the respective material. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.
          References
          Product Information
          HS Code3824 99 92
          Quality LevelMQ400
          Applications
          ApplicationSolution for rapid decalcification (with fixation) for histology
          Biological Information
          Physicochemical Information
          Density1.10 g/cm3 (20 °C)
          pH value1 (H₂O, 20 °C)
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Hazard Pictogram(s) Hazard Pictogram(s)
          Hazard Pictogram(s)
          Hazard Pictogram(s)
          Hazard Statement(s)H290: Poate fi corosiv pentru metale.
          H302 + H332: Nociv în caz de înghiţire sau inhalare.
          H314: Provoacă arsuri grave ale pielii şi lezarea ochilor.
          H317: Poate provoca o reacţie alergică a pielii.
          H335: Poate provoca iritarea căilor respiratorii.
          H341: Susceptibil de a provoca anomalii genetice.
          H350: Poate provoca cancer.
          Precautionary Statement(s)P202: A nu se manipula decât după ce au fost citite şi înţelese toate măsurile de securitate.
          P280: Purtați mănuși de protecție/ îmbrăcăminte de protecție/ protecție pentru ochi/ protecție pentru față/ protecție pentru auz.
          P301 + P312: ÎN CAZ DE ÎNGHIȚIRE: Sunați la un CENTRU DE INFORMARE TOXICOLOGICĂ/un medic dacă nu vă simțiți bine.
          P303 + P361 + P353: ÎN CAZ DE CONTACT CU PIELEA (sau cu părul): Scoateți imediat toată îmbrăcămintea contaminată. Clătiți pielea cu apă.
          P304 + P340 + P310: ÎN CAZ DE INHALARE: transportați persoana la aer liber și mențineți-o într-o poziție confortabilă pentru respirație. Sunați imediat la un CENTRU DE INFORMARE TOXICOLOGICĂ/un medic.
          P305 + P351 + P338: ÎN CAZ DE CONTACT CU OCHII: Clătiți cu atenție cu apă timp de mai multe minute. Scoateți lentilele de contact, dacă este cazul și dacă acest lucru se poate face cu ușurință. Continuați să clătiți.
          Signal WordPericol
          Storage class6.1D Materiale necombustibile, toxicitate acută Categoria 3/ materiale periculoase toxice sau materiale periculoase provocând efecte cronice
          WGKWGK 3 puternică poluare a apei
          Disposal9
          Compusii cancerigeni si compusii inflamabili marcati ca "toxici" sau "foarte toxici": container F. Alchili-sulfatii sunt cancerigeni. Luati masuri speciale pentru a evita inhalarea sau contactul cu pielea. Pentru neutralizarea alchil-sulfatilor, acestia se adauga in picaturi (cu o palnie de picurare) in solutie concentrata de amoniac racita cu gheata (Cod Merck 105426) agitand puternic. Inainte de colectarea in containerul D, verificati pH-ul cu strip-uri indicatoare pH, universale (Cod Merck 109535).
          Safety Information
          Categories of dangernociv, iritant, carcinogen, sensibilizator
          Product Usage Statements
          Storage and Shipping Information
          StorageA se depozita între +15°C la +25°C.
          Packaging Information
          Transport Information
          Declaration (railroad and road) ADR, RIDUN 1789 , 8, II
          Declaration (transport by air) IATA-DGRUN 1789 , 8, II
          Declaration (transport by sea) IMDG-CodeUN 1789 , 8, II, Segregation Group: 1 (Acids)
          Supplemental Information
          Specifications
          Performance testpasses test
          Global Trade Item Number
          Catalogue Number GTIN
          1017361000 04022536929026
          1017362500 04027269233082

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          Categories

          IVD/OEM Materials & Reagents > Microscopy > Histology > Auxiliaries for Histology
          IVD/OEM Materials & Reagents > Microscopy > Universal Reagents > Decalcification