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454575 N-Methyl-D-aspartic Acid, Hydrate - CAS 6384-92-5 - Calbiochem

Excitatory amino acid neurotransmitter.

N-Methyl-D-aspartic Acid, Hydrate - CAS 6384-92-5 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: NMDA

Primary Target: Glutamate receptor that regulates Ca2+ channels
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454575
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
6384-92-5C₅H₉NO₄•H₂O

Pricing & Availability

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454575-100MG
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      		 Plastic ampoule 100 mg
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      Description
      OverviewExcitatory amino acid neurotransmitter. Selective agonist of the glutamate receptor that regulates Ca2+ channels. Important in long-term potentiation, ischemia, and epilepsy. NMDA receptors are involved in the "fine tuning" of synaptic connections in the developing brain. Chronic treatment with NMDA produces structural changes in synaptic morphology. Over-excitation of NMDA receptors causes neuronal degeneration and cell death.
      Catalogue Number454575
      Brand Family Calbiochem®
      SynonymsNMDA
      References
      ReferencesMattson, M.P., et al. 1993. J. Neurosci. 13, 4575.
      Yen, L-H., et al. 1993. J. Neurosci. 13, 4949.
      Swann, J.W., et al. 1992. Epilepsy Res. Suppl. 9, 115.
      Product Information
      CAS number6384-92-5
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₅H₉NO₄•H₂O
      Chemical formulaC₅H₉NO₄•H₂O
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetGlutamate receptor that regulates Ca2+ channels
      Purity>95% by TLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSCI9457000
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +15°C to +30°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for several days at 4°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      454575-100MG 04055977204148

      Documentation

      N-Methyl-D-aspartic Acid, Hydrate - CAS 6384-92-5 - Calbiochem MSDS

      Title

      Safety Data Sheet (SDS) 

      N-Methyl-D-aspartic Acid, Hydrate - CAS 6384-92-5 - Calbiochem Certificates of Analysis

      TitleLot Number
      454575

      References

      Reference overview
      Mattson, M.P., et al. 1993. J. Neurosci. 13, 4575.
      Yen, L-H., et al. 1993. J. Neurosci. 13, 4949.
      Swann, J.W., et al. 1992. Epilepsy Res. Suppl. 9, 115.

      Brochure

      Title
      Excitotoxic Glutamate Analogs Technical Bulletin
      Pathways and Biomarkers of Glutamatergic Synapse Flyer
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision30-August-2007 JSW
      SynonymsNMDA
      DescriptionAn excitatory amino acid neurotransmitter. Selective agonist of the glutamate receptor that regulates Ca2+ channels. Important in long-term potentiation, ischemia, and epilepsy. NMDA receptors are involved in the "fine tuning" of synaptic connections in the developing brain. Chronic treatment with NMDA produces structural changes in synaptic morphology. Over-excitation of NMDA receptors causes neuronal degeneration and cell death.
      FormWhite solid
      CAS number6384-92-5
      RTECSCI9457000
      Chemical formulaC₅H₉NO₄•H₂O
      Structure formulaStructure formula
      Purity>95% by TLC
      SolubilityH₂O (1 mg/ml)
      Storage +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for several days at 4°C.
      Toxicity Standard Handling
      Merck USA index14, 6662
      ReferencesMattson, M.P., et al. 1993. J. Neurosci. 13, 4575.
      Yen, L-H., et al. 1993. J. Neurosci. 13, 4949.
      Swann, J.W., et al. 1992. Epilepsy Res. Suppl. 9, 115.