Mobius® Breez Microbioreactor
A 2 mL Automated Perfusion Cell Culture Platform to Accelerate Your Development Timeline
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A 2 mL Automated Perfusion Cell Culture Platform to Accelerate Your Development Timeline Less
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Overview
The Mobius® Breez Microbioreactor is a 2 mL automated single-use perfusion cell culture platform designed to support gentle, adaptable, and reproducible cell processes. The system is capable of accelerating a range of applications such as cell line development, media screening and optimization, and early process development.
The Mobius® Breez Microbioreactor allows you to increase efficiency and reduce development timelines and costs over traditional technologies that require more material consumption. The platform comprises gamma-irradiated microbioreactor consumables with integrated fluid supply, four (4) bioreactor controllers (PODs), accompanying hardware and intuitive software. Each POD provides closed loop control for pH, DO, temperature, and cell density via OD. With the Mobius® Breez Microbioreactor, readily run 4 experiments simultaneously and independently on your benchtop. Total control is at your fingertips to help support your development program and company goals, ensuring timely delivery of high-quality data sets you can rely on.
Key Benefits
- Enables perfusion processes to achieve high cell densities in 2 mL
- Run more experiments in parallel for higher productivity
- Reliable, high-quality product on demand
- Freedom from process limitations using automated control and monitoring
- Operational flexibility allows you to save on development time and costs
- Easy to use and install, allowing you to focus on your goals
Modalities
- Monoclonal antibodies
- Recombinant proteins
- Cell therapy
Specifications
| Consumable | |
| Materials of Construction | Main Cassette: Polycarbonate, Silicone, Polyethersulfone, PETG, Acrylic PSA, Silicone PSA Bottleset: C-Flex, Polycarbonate, Silicone, PETG, ETFE, PVDF, ABS, Polypropylene, HDPE, Polyurethane, (PVC) |
| Dimensions | For Tubing from Bottle to Cassette: Length Approx. 27" User connect tubing (C-Flex): Length Approx. 18", 1/4" OD, 1/8" ID User connect tubing (PVC): Length Approx. 18", 5/32" OD, 3/32" ID |
| Microbioreactor working volume | 2.155 mL |
| Number of Fluid Inputs | 4 (one is reserved for DI water) |
| Number of Fluid Outputs | 3 (sample, cell waste, perfusion harvest) |
| Flow Rate Range | 0.1 - 10 VVD |
| Hardware | |
| Materials of Construction | Basestation: anodized aluminum, stainless steel, silicone, C-flex, PVC, copolyester, polypropylene, vinyl CO2 Box: anodized aluminum, vinyl, chrome/nickel plated brass, stainless steel POD: anodized aluminum, acetyl (Delrin), stainless steel, vinyl, silicone, C-flex, solder mask, nickel plated copper, polycarbonate |
| Dimensions (W x H x D) | Minimum Space W (with laptop): 26 in. (66 cm) W (without laptop): 14 in. (36 cm) H: 16 in. (41 cm) D: 20 in. (51 cm) |
| Weight | As Installed (w/ Accessories): Approx. 60 lbs. (27 kg) |
| List of inputs/outputs | Gas Input: Air, N2, O2, CO2 Gas Output: Mixed air (Air, N2, O2, and CO2) Electrical input: 2x 24VDC inputs |
Ordering Information
Documentation
Related Products & Applications
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| Consumable | |
| Materials of Construction | Main Cassette: Polycarbonate, Silicone, Polyethersulfone, PETG, Acrylic PSA, Silicone PSA Bottleset: C-Flex, Polycarbonate, Silicone, PETG, ETFE, PVDF, ABS, Polypropylene, HDPE, Polyurethane, (PVC) |
| Dimensions | For Tubing from Bottle to Cassette: Length Approx. 27" User connect tubing (C-Flex): Length Approx. 18", 1/4" OD, 1/8" ID User connect tubing (PVC): Length Approx. 18", 5/32" OD, 3/32" ID |
| Microbioreactor working volume | 2.155 mL |
| Number of Fluid Inputs | 4 (one is reserved for DI water) |
| Number of Fluid Outputs | 3 (sample, cell waste, perfusion harvest) |
| Flow Rate Range | 0.1 - 10 VVD |
| Hardware | |
| Materials of Construction | Basestation: anodized aluminum, stainless steel, silicone, C-flex, PVC, copolyester, polypropylene, vinyl CO2 Box: anodized aluminum, vinyl, chrome/nickel plated brass, stainless steel POD: anodized aluminum, acetyl (Delrin), stainless steel, vinyl, silicone, C-flex, solder mask, nickel plated copper, polycarbonate |
| Dimensions (W x H x D) | Minimum Space W (with laptop): 26 in. (66 cm) W (without laptop): 14 in. (36 cm) H: 16 in. (41 cm) D: 20 in. (51 cm) |
| Weight | As Installed (w/ Accessories): Approx. 60 lbs. (27 kg) |
| List of inputs/outputs | Gas Input: Air, N2, O2, CO2 Gas Output: Mixed air (Air, N2, O2, and CO2) Electrical input: 2x 24VDC inputs |