Millipore Sigma Vibrant Logo

817058 Acid maleic

EMPROVE® ESSENTIAL Ph Eur,NF

Acid maleic MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: cis-Butenedioic acid

CAS #: 110-16-7 EC Number: 203-742-5 Molar Mass: 116.07 g/mol Chemical Formula: HOOCCH=CHCOOH Hill Formula: C₄H₄O₄ Grade: Ph Eur,NF
View Products on Sigmaaldrich.com
817058
View Pricing & Availability
Learn about the Emprove® Program

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
110-16-7203-742-5C₄H₄O₄HOOCCH=CHCOOH116.07 g/molPh Eur,NF

Pricing & Availability

Catalogue Number AvailabilityPackaging Qty/Pack Price Quantity
8170581000
Retrieving availability...
—
Limited Availability Limited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      		 1 kg
      Retrieving price...
      Price could not be retrieved
      Minimum Quantity is a multiple of
      Maximum Quantity is
      Upon Order Completion More Information
      You Saved ()
       
      —
      Request Pricing
      		 —
      8170589025
      Retrieving availability...
      —
      Limited Availability Limited Availability
      In Stock 
      Discontinued
      Limited Quantities Available
      Availability to be confirmed
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service
          Contact Customer Service

          		 Fibre carton 25 kg
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity is a multiple of
          Maximum Quantity is
          Upon Order Completion More Information
          You Saved ()
           
          —
          Request Pricing
          		 —
          Description
          Catalogue Number817058
          Synonymscis-Butenedioic acid
          DescriptionMaleic acid suitable for use as excipient
          References
          Product Information
          CAS number110-16-7
          EC index number607-095-00-3
          EC number203-742-5
          GradePh Eur,NF
          Hill FormulaC₄H₄O₄
          Chemical formulaHOOCCH=CHCOOH
          Molar Mass116.07 g/mol
          HS Code2917 19 90
          Structure formula ImageStructure formula Image
          Quality LevelMQ500
          Applications
          Biological Information
          Physicochemical Information
          Density1.59 g/cm3 (20 °C)
          Melting Point130 - 135 °C
          pH value1.3 (100 g/l, H₂O, 20 °C)
          Vapor pressure<0.1 hPa (20 °C)
          Bulk density750 - 800 kg/m3
          Solubility478.8 g/l
          Dimensions
          Materials Information
          Toxicological Information
          LD 50 oralLD50 Rat 708 mg/kg
          LD 50 dermalLD50 Rabbit 1560 mg/kg
          Safety Information according to GHS
          Hazard Pictogram(s) Hazard Pictogram(s)
          Hazard Pictogram(s)
          Hazard Statement(s)H302 + H312: Nociv în caz de înghițire sau în contact cu pielea.
          H314: Provoacă arsuri grave ale pielii şi lezarea ochilor.
          H317: Poate provoca o reacţie alergică a pielii.
          H335: Poate provoca iritarea căilor respiratorii.
          Precautionary Statement(s)P260: Nu inspiraţi praful.
          P271: A se utiliza numai în aer liber sau în spaţii bine ventilate.
          P280: Purtați mănuși de protecție/ îmbrăcăminte de protecție/ protecție pentru ochi/ protecție pentru față/ protecție pentru auz.
          P301 + P312: ÎN CAZ DE ÎNGHIȚIRE: Sunați la un CENTRU DE INFORMARE TOXICOLOGICĂ/un medic dacă nu vă simțiți bine.
          P303 + P361 + P353: ÎN CAZ DE CONTACT CU PIELEA (sau cu părul): Scoateți imediat toată îmbrăcămintea contaminată. Clătiți pielea cu apă.
          P305 + P351 + P338: ÎN CAZ DE CONTACT CU OCHII: Clătiți cu atenție cu apă timp de mai multe minute. Scoateți lentilele de contact, dacă este cazul și dacă acest lucru se poate face cu ușurință. Continuați să clătiți.
          Signal WordPericol
          RTECSOM9625000
          Storage class8A Materiale periculoase corozive, combustibile
          WGKWGK 1 slabă contaminare a apei
          Disposal3
          Reactivii organici relativ cu reactivitate relativ redusa trebuie colectati in containerul A. Daca sunt halogenati, ei trebuie colectati in containerul B. Pentru reziduurile solide utilizati containerul C.
          Safety Information
          Categories of dangernociv, iritant, sensibilizator
          Product Usage Statements
          Storage and Shipping Information
          StorageA se depozita între +15°C la +25°C.
          Packaging Information
          Transport Information
          Declaration (railroad and road) ADR, RIDUN 3261 , 8, II
          Declaration (transport by air) IATA-DGRUN 3261 , 8, II
          Declaration (transport by sea) IMDG-CodeUN 3261 , 8, II, Segregation Group: 1 (Acids)
          Supplemental Information
          Specifications
          Assay (calc.on anhydrous substance)99.0 - 101.0 %
          Assay (HPLC, calc. on anhydrous substance)98.0 - 102.0 %
          Identity (wet chemistry)passes test
          Identity (HPLC)passes test
          Identity (pH)passes test
          Identity (TLC)passes test
          Identity (IR)passes test
          Appearance of solutionpasses test
          Fe (Iron)≤ 5 ppm
          V (Vanadium)*≤ 1 ppm
          Fumaric acid (TLC)≤ 1.5 %
          Fumaric acid (HPLC)≤ 1.0 %
          Malic acid (HPLC)≤ 0.5 %
          Residual solvents (ICH Q3C)excluded by the production process
          Sulfated ash≤ 0.1 %
          Water (K. F.)≤ 0.5 %
          Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
          Corresponds to Ph Eur, NF
          Global Trade Item Number
          Catalogue Number GTIN
          8170581000 04022536548777
          8170589025 04022536648118

          Documentation

          Emprove Dossier

          TitleVersion
          8.0

          Quality Management Dossier (Open Access)

          Title

          Operational Excellence Dossier

          Title

          Acid maleic MSDS

          Title

          Safety Data Sheet (SDS) 

          Acid maleic Certificates of Analysis

          Product Number PackagingSpecificationLot Number
          8170581000 PDF Specification Document
          8170589025 Fibre cartonPDF Specification Document

          Certificates

          Title

          Related Products & Applications

          Categories

          Small Molecule Pharmaceuticals > Formulation > Solid Dosage Form > pH Adjustment
          Small Molecule Pharmaceuticals > Formulation > Semisolid Dosage Form > Acidulants and pH Adjustments
          Reagents, Chemicals and Labware > Organic Synthesis > Organic Synthesis Product Groups > Carboxylic Acids > Di-and Polycarboxylic Acids
          Biopharmaceutical Manufacturing > Formulation > Liquid Dosage > pH Adjustments and Isotonizers
          Reagents, Chemicals and Labware > Organic Synthesis > Organic Synthesis Products for Pharma > Organic Synthesis Building Blocks and Reagents for Pharma > Carboxylic Acids > Di-and Polycarboxylic Acids
          Small Molecule Pharmaceuticals > Formulation > Liquid Dosage Form > pH Adjustments and Isotonizers