Skip to Content
Merck

Key Documents

View All Documentation

HNDG2MAG-36K

MILLIPLEX® Human Neurodegenerative Disease Panel

Configurable Human Neurodegenerative Disease 6-Plex Panel 2

Sign In to View Organizational & Contract Pricing.

About This Item

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

Product Name

MILLIPLEX® Human Neurodegenerative Disease Panel,

description

Configurable Human Neurodegenerative Disease 6-Plex Panel 2

Quality Segment

200

species reactivity

human

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

assay range

accuracy: 84%
(SAP), accuracy: 88%
(Complement C4), accuracy: 92%
(α-1-Antitrypsin), accuracy: 92%
(PEDF), accuracy: 95%
(MIP-4), standard curve range: 0.05-200 ng/mL
(PEDF), standard curve range: 0.10-50 ng/mL
(CRP), standard curve range: 0.12-500 ng/mL
(SAP), standard curve range: 0.24-1,000 ng/mL
(α-1-Antitrypsin), standard curve range: 0.24-1,000 ng/mL
(Complement C4), standard curve range: 4.88-20,000 ng/mL
(MIP-4)

technique(s)

multiplexing: suitable

input

cerebrospinal fluid (CSF)
serum
plasma
cell culture supernatant(s)

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

Inflammatory cascades in the brain are shaped by acute phase proteins and complement activity. CRP and SAP accumulate in amyloid plaques and signal systemic inflammation. α1-Antitrypsin tempers protease activity and may dampen microglial overactivation, offering a protective buffer against amyloid-beta toxicity. PEDF contributes neuroprotective and anti-angiogenic effects, while complement C4 supports immune surveillance and debris clearance in neurodegenerative contexts.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 6 analytes in human serum, plasma, and cerebrospinal fluid (CSF).

Analytes included: CRP, α1-antitrypsin, PEDF, SAP, MIP-4, Complement C4.

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

  • Acute Phase Response Profiling: Simultaneously quantify CRP, SAP, and α1-antitrypsin to capture comprehensive inflammatory responses and immune system activation patterns critical for neurodegeneration research.
  • Sample Type Flexibility: Analyze serum, plasma, and cerebrospinal fluid samples with validated performance, enabling comprehensive biomarker studies across diverse biological specimens and research applications.
  • Batch-to-Batch Consistency: Trust in stringent manufacturing standards and quality controls that ensure reproducible results across different kit lots, supporting longitudinal studies and multi-site collaborations.
  • Expert Scientific Partnership: Access dedicated field application scientists and technical support teams who provide can specialized multiplex assay guidance.
  • Configurable Research Solutions: Design your ideal biomarker panel by selecting any combination of the 6 analytes, creating tailored assays that perfectly align with your specific research hypotheses and objectives.

Legal Information

Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Still not finding the right product?

Explore all of our products under MILLIPLEX® Human Neurodegenerative Disease Panel

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

Storage Class

10 - Combustible liquids

wgk

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library