Millipore Sigma Vibrant Logo

105988 D(-)-Manitol

pulbere fina EMPROVE® ESSENTIAL Ph Eur,BP,USP,JP,FCC,E 421

D(-)-Manitol MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 69-65-8 EC Number: 200-711-8 Molar Mass: 182.17 g/mol Hill Formula: C₆H₁₄O₆ Grade: Ph Eur,BP,USP,JP,FCC,E 421
View Products on Sigmaaldrich.com
105988
View Pricing & Availability
Learn about the Emprove® Program

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
69-65-8200-711-8C₆H₁₄O₆182.17 g/molPh Eur,BP,USP,JP,FCC,E 421

Pricing & Availability

Catalogue Number AvailabilityPackaging Qty/Pack Price Quantity
1059881000
Retrieving availability...
—
Limited Availability Limited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      		 Plastic bottle 1 kg
      Retrieving price...
      Price could not be retrieved
      Minimum Quantity is a multiple of
      Maximum Quantity is
      Upon Order Completion More Information
      You Saved ()
       
      —
      Request Pricing
      		 —
      1059889024
      Retrieving availability...
      —
      Limited Availability Limited Availability
      In Stock 
      Discontinued
      Limited Quantities Available
      Availability to be confirmed
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service
          Contact Customer Service

          		 Double PE Sack 20 kg
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity is a multiple of
          Maximum Quantity is
          Upon Order Completion More Information
          You Saved ()
           
          —
          Request Pricing
          		 —
          Description
          Catalogue Number105988
          References
          Product Information
          CAS number69-65-8
          EC number200-711-8
          GradePh Eur,BP,USP,JP,FCC,E 421
          Hill FormulaC₆H₁₄O₆
          Molar Mass182.17 g/mol
          HS Code2905 43 00
          Structure formula ImageStructure formula Image
          Quality LevelMQ500
          Applications
          Biological Information
          Physicochemical Information
          Boiling point290 - 295 °C (4 hPa)
          Density1.52 g/cm3 (20 °C)
          Ignition temperature410 °C
          Melting Point164 - 169 °C
          pH value5.0 - 6.5 (182 g/l, H₂O, 25 °C)
          Bulk density400 - 500 kg/m3
          Solubility213 g/l
          Dimensions
          Materials Information
          Toxicological Information
          LD 50 oralLD50 Rat 13500 mg/kg
          Safety Information according to GHS
          RTECSOP2060000
          Storage class10 - 13 Alte lichide sau solide
          WGKWGK 1 slabă contaminare a apei
          Disposal3
          Reactivii organici relativ cu reactivitate relativ redusa trebuie colectati in containerul A. Daca sunt halogenati, ei trebuie colectati in containerul B. Pentru reziduurile solide utilizati containerul C.
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          StorageA se depozita între +2°C la +25°C.
          Packaging Information
          Transport Information
          Declaration (railroad and road) ADR, RIDKein Gefahrgut
          Declaration (transport by air) IATA-DGRNo Dangerous Good
          Declaration (transport by sea) IMDG-CodeNo Dangerous Good
          Supplemental Information
          Specifications
          Assay (HPLC, calc. on dried substance)98.0 - 101.0 %
          Identity (NIR)passes test
          Appearance of solution (10 %; water)passes test
          pH-value (10 %; water)4.5 - 7.5
          Melting point165 - 169
          Conductivity (25°C) (20 %; water)≤ 20
          Heavy metals (as Pb)≤ 5 ppm
          Ni (Nickel) (#)≤ 1 ppm
          Pb (Lead)≤ 0.5 ppm
          Related substances (HPLC) (Sorbitol (Impurity A))≤ 2.0 %
          Related substances (HPLC) (Sum of Maltitol and Isomalt (Impurities B and C))≤ 2.0
          Related substances (HPLC) (Major unspecified impurity)≤ 0.10 %
          Related substances (HPLC) (Sum of all impurities)≤ 2.0 %
          Reducing sugars (as glucose)≤ 0.05
          Reducing sugars after hydrolysis/total sugar (as glucose)≤ 1
          Sulfated ash≤ 0.1
          Water≤ 0.5 %
          Loss on Drying (105 °C)≤ 0.30 %
          Particle size (> 150 µm)≤ 2 %
          Residual solvents (ICH Q3C)excluded by manufacturing process
          Microbiological testpasses test
          Colony count (aerobic bacteria (TAMC))≤ 10³
          Colony count (Yeasts and moulds (TYMC))≤ 10²
          Salmonella spp.in 10g Substance not detectable
          E.coliin 1g Substance not detectable
          Staphylococcus aureusin 1g Substance not detectable
          Pseudomonas aeruginosain 1g Substance not detectable
          Candida albicansIn 1g Substance not detectable
          Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities).
          Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (#).
          Corresponds to Ph. Eur., BP, USP, JP, FCC, E 421
          Conforms to the purity criteria on food additives according to the current European Commission Regulation.
          Global Trade Item Number
          Catalogue Number GTIN
          1059881000 04022536961385
          1059889024 04022536934037

          Documentation

          Emprove Dossier

          TitleVersion
          8.0

          Quality Management Dossier (Open Access)

          Title

          Operational Excellence Dossier

          Title

          D(-)-Manitol MSDS

          Title

          Safety Data Sheet (SDS) 

          D(-)-Manitol Certificates of Analysis

          Product Number PackagingSpecificationLot Number
          1059881000 Plastic bottlePDF Specification Document
          1059889024 Double PE SackPDF Specification Document

          Certificates

          Title

          Related Products & Applications

          Related Products By: Application Facete

          Binders and Fillers
          Tonicity Agents
          Surfactants and Stabilizers

          Related Products By: Brand Facete

          EMPROVE®

          Categories

          Biopharmaceutical Manufacturing > Formulation > Liquid Dosage > Surfactants and Stabilizers
          Small Molecule Pharmaceuticals > Formulation > Solid Dosage Form > Binders and Fillers
          Biopharmaceutical Manufacturing > Formulation > Liquid Dosage > Tonicity Agents
          Small Molecule Pharmaceuticals > Formulation > Liquid Dosage Form > Tonicity Agents
          Small Molecule Pharmaceuticals > Formulation > Liquid Dosage Form > Surfactants and Stabilizers