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208922 CaMKII Inhibitor, CK59 - CAS 140651-18-9 - Calbiochem

The CaMKII Inhibitor, CK59, also referenced under CAS 140651-18-9, controls the biological activity of CaMKII. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

CaMKII Inhibitor, CK59 - CAS 140651-18-9 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 2-(2-Hydroxyethylamino)-6-aminohexylcarbamic acid tert-butyl ester-9-isopropylpurine, CK59

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208922
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
140651-18-9C₂₁H₃₇N₇O₃

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      Description
      OverviewA cell-permeable Olomoucine (Cat. Nos. 495620 & 495624) analog that acts as a CaMKII inhibitor (IC50 <10 µM) and inhibits insulin-stimulated glucose uptake (IC50 ≤5 µM) and GLUT4 membrane translocation (IC50 = 100 µM) in 3T3-L1 adipocytes.
      Catalogue Number208922
      Brand Family Calbiochem®
      Synonyms2-(2-Hydroxyethylamino)-6-aminohexylcarbamic acid tert-butyl ester-9-isopropylpurine, CK59
      References
      ReferencesKonstantopoulos, N., et al. 2007. Endocrinology, 148, 374.
      Product Information
      CAS number140651-18-9
      FormYellow semi-solid
      Hill FormulaC₂₁H₃₇N₇O₃
      Chemical formulaC₂₁H₃₇N₇O₃
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot, and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      208922-5MG 04055977219104

      Documentation

      CaMKII Inhibitor, CK59 - CAS 140651-18-9 - Calbiochem MSDS

      Title

      Safety Data Sheet (SDS) 

      CaMKII Inhibitor, CK59 - CAS 140651-18-9 - Calbiochem Certificates of Analysis

      TitleLot Number
      208922

      References

      Reference overview
      Konstantopoulos, N., et al. 2007. Endocrinology, 148, 374.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision19-February-2014 JSW
      Synonyms2-(2-Hydroxyethylamino)-6-aminohexylcarbamic acid tert-butyl ester-9-isopropylpurine, CK59
      DescriptionA cell-permeable Olomoucine (Cat. Nos. 495620 & 495624) analog that acts as a CaMKII inhibitor (IC50 <10 µM) and inhibits insulin-stimulated glucose uptake (IC50 ≤5 µM) and GLUT4 membrane translocation (IC50 = 100 µM) in 3T3-L1 adipocytes.
      FormYellow semi-solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number140651-18-9
      Chemical formulaC₂₁H₃₇N₇O₃
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (10 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot, and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesKonstantopoulos, N., et al. 2007. Endocrinology, 148, 374.