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236603 C-Reactive Protein, Human Serum, High Purity

C-Reactive Protein, Human Serum, High Purity, CAS 9007-41-4, is a major acute-phase plasma protein. Useful as a calibration standard for assays of CRP and as an antigen for production of antisera.

C-Reactive Protein, Human Serum, High Purity MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: CRP

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236603
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236603-100UG
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      Description
      OverviewNative C-reactive protein highly purified from human serum. CRP is a major acute-phase plasma protein that is dramatically elevated in patients with acute-phase conditions. Composed of five identical noncovalently linked subunits. Exhibits Ca2+-dependent binding to a variety of substrates. Important in diagnosis of rheumatoid arthritis. Suitable for immunological studies. In purified states and in plasma the monomeric form (M.W. ~21 kDa) aggregates as a cyclic pentamer. Intended for use as a calibration standard for assays of CRP, for structural and functional studies, and as an antigen for production of antisera. Calibrated by electroimmunoassay against WHO reference standard or equivalent.
      No reaction in ODD and Laurell electroimmunoassay against polyvalent antiserum to normal human serum, antiserum to pooled effusion fluids and monospecific antiserum to human IgG.
      M.W. 23,000 (monomer); 115,000 (pentamer).
      Catalogue Number236603
      Brand Family Calbiochem®
      SynonymsCRP
      References
      ReferencesPaffen, E., et al. 2004. Arterioscler. Thromb. Vasc. Biol. 24, 975.
      Product Information
      CAS number9007-41-4
      FormLiquid
      FormulationIn 140 mM NaCl, 10 mM Tris, 2 mM CaCl₂, 0.1% NaN₃, pH 8.0.
      Quality LevelMQ100
      Biological Information
      Purity≥99% by SDS-PAGE
      SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Global Trade Item Number
      Catalogue Number GTIN
      236603-100UG 04055977217186