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MABS441 Anti-WBP2 Antibody, clone 4C8H10

This Anti-WBP2 Antibody, clone 4C8H10 is validated for use in Western Blotting and Immunoprecipitation and Immunocytochemistry and Immunohistochemistry for the detection of WBP2.

Anti-WBP2 Antibody, clone 4C8H10 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling, Apoptosis & Cancer Research Sub-Category: Growth Factors & Receptors Gene Symbol: WBP2 UniProt Number: Q969T9
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MABS441
100 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IP, ICC, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABS441
      DescriptionAnti-WBP2 Antibody, clone 4C8H10
      Alternate Names
      • WW domain-binding protein 2
      • WBP-2
      Background InformationWBP2 is a protein-protein interacting protein that binds to the WW domain of YAP1, WWP1 and WWP2 proteins. WW domain-containing proteins are found in most cells and play important roles in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. They are also upregulated in many cancers. WBP2 also interacts with the ubiquitin ligase proteins belonging to the NEDD4 family and appears to assist in the regulation of targeting proteins to proteasomes or lysosomes. Also in WBP2 knockout mice, the mice display abnormal brainstem and hearing development, indicating an important role in development as well.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-WBP2 Antibody, clone 4C8H10 is validated for use in Western Blotting and Immunoprecipitation and Immunocytochemistry and Immunohistochemistry for the detection of WBP2.
      Key Applications
      • Western Blotting
      • Immunoprecipitation
      • Immunocytochemistry
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A representative lot detected WBP2 in breast cancer tissue at 1.25 ug/ml
      Immunocytochemistry Analysis: A representative lot detected WBP2 in transfected HeLa cell fixed with 4% paraformaldehyde at 20 ug/ml
      Immunoprecipitation Analysis: A representative lot immunoprecipitated transfected V5-WBP2 from HeLa cell
      Biological Information
      ImmunogenGST-tagged full length recombinant protein corresponding to Human WBP2.
      Clone4C8H10
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • WBP2
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~ 37 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in MDA-MB-231 cell lysate.

      Western Blotting Analysis: 2.0 µg/mL of this antibody detected WBP2 in 10 µg of MDA-MB-231 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABS441 04055977039542