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AB5871 Anti-SNAP-25 Antibody

Anti-SNAP-25 Antibody is an antibody against SNAP-25 for use in IP, WB, IH.

Anti-SNAP-25 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Synapse & Synaptic Biology Gene Symbol: SNAP25, SNAP, dJ1068F16.2, SNAP-25, FLJ23079, RIC-4, SUP, SEC9, RIC4, bA416N4.2 UniProt Number: P60880
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AB5871
50 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HIP, WB, IHCGtPurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB5871
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-SNAP-25 Antibody
      Alternate Names
      • Synaptosomal-associated Protein 25
      References
      Product Information
      FormatPurified
      PresentationIgG fraction (protein A) in PBS with 50% Glycerol and 0.01% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-SNAP-25 Antibody is an antibody against SNAP-25 for use in IP, WB, IH.
      Key Applications
      • Immunoprecipitation
      • Western Blotting
      • Immunohistochemistry
      Application NotesWestern blot: 1:100 - 1:2000
      ELISA: 1:1000 - 1:100,000
      Immunohistochemistry: 1:50 - 1:100

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenRecombinant human SNAP-25
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostGoat
      SpecificitySNAP-25
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummarySynaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
      Gene Symbol
      • SNAP25
      • SNAP
      • dJ1068F16.2
      • SNAP-25
      • FLJ23079
      • RIC-4
      • SUP
      • SEC9
      • RIC4
      • bA416N4.2
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P60880 # t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion.
      SIZE: 206 amino acids; 23315 Da
      SUBUNIT: Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. This complex binds CPLX1. Interacts with TRIM9, RIMS1, SNAP25BP and HGS. Binds STXBP6. Found in a ternary complex with STX1A and VAMP8. Found in a complex containing SYT1, SV2B and syntaxin-1 (By similarity).
      TISSUE SPECIFICITY: Neurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum.
      PTM: Palmitoylated (By similarity).
      SIMILARITY: SwissProt: P60880 ## Belongs to the SNAP-25 family. & Contains 2 t-SNARE coiled-coil homology domains.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C in undiluted for up to 6 months from date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size50 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      AB5871 04053252738821

      Documentation

      Anti-SNAP-25 Antibody MSDS

      Title

      Safety Data Sheet (SDS) 

      Anti-SNAP-25 Antibody Certificates of Analysis

      TitleLot Number
      GOAT ANTI-SNAP-25 POLYCLONAL ANTIBODY - 2119726 2119726
      GOAT ANTI-SNAP-25 POLYCLONAL ANTIBODY - 2426496 2426496
      GOAT ANTI-SNAP-25 - 2558365 2558365
      GOAT ANTI-SNAP-25 - 3194683 3194683
      GOAT ANTI-SNAP-25 - 3222657 3222657
      GOAT ANTI-SNAP-25 - 3421945 3421945
      GOAT ANTI-SNAP-25 POLYCLONAL ANTIBODY 2914550
      GOAT ANTI-SNAP-25 POLYCLONAL ANTIBODY -
      GOAT ANTI-SNAP-25 POLYCLONAL ANTIBODY - 2092619 2092619
      GOAT ANTI-SNAP-25 POLYCLONAL ANTIBODY - 2108481 2108481
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      Brochure

      Title
      Pathways and Biomarkers of Glutamatergic Synapse Flyer

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies