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MAB5260Z Anti-Nerve Growth Factor Antibody, clone 27/21, azide free

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MAB5260Z
25 µg  
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      Overview

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      B, H, M, RELISA, NEUTMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMAB5260Z
      Replaces04-1119
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Nerve Growth Factor Antibody, clone 27/21, azide free
      Alternate Names
      • NGF
      • MAB5260
      Product Information
      FormatPurified
      Control
      • Brain tissue
      PresentationProtein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with no preservatives.
      Quality LevelMQ100
      Applications
      ApplicationDetect Nerve Growth Factor using this Anti-Nerve Growth Factor Antibody, clone 27/21, azide free validated for use in ELISA, NEUT.
      Key Applications
      • ELISA
      • Neutralizing
      Application NotesThe antibody is used for the neutralization of NGF in cell culture systems. Furthermore the antibody is used to immunosympathectomy.

      Optimal working dilutions must be determined by end user.
      Biological Information
      Immunogen2.5 S form of mouse NGF.
      Clone27/21
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificitySpecifically reacts with the beta -subunit of NGF from mouse, in the 2.5S- as well as in the 7S-form.
      IsotypeIgG1
      Species Reactivity
      • Bovine
      • Human
      • Mouse
      • Rat
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.
      Gene Symbol
      • NTF3
      • NT3
      • NGF2
      • HDNF
      • MGC129711
      • NGF-2
      • NT-3
      Purification MethodProtein A Purfied
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P20783 # Seems to promotes the survival of visceral and proprioceptive sensory neurons.
      SIZE: 257 amino acids; 29355 Da
      SUBCELLULAR LOCATION: Secreted.
      TISSUE SPECIFICITY: Brain and peripheral tissues.
      SIMILARITY: SwissProt: P20783 ## Belongs to the NGF-beta family.
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain for 6 months at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
      Packaging Information
      Material Size25 µg
      Global Trade Item Number
      Catalogue Number GTIN
      MAB5260Z 04053252316821