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AB9141 Anti-Dopamine Receptor D1 Antibody

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AB9141
50 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HIH(P)RbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB9141
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Dopamine Receptor D1 Antibody
      References
      Product Information
      FormatAffinity Purified
      HS Code3002 15 90
      PresentationAffinity purified immunoglobulin. Liquid in PBS, pH 7.7 with 0.01% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Dopamine Receptor D1 Antibody is validated for use in IH(P) for the detection of Dopamine Receptor D1.
      Key Applications
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry on formalin fixed paraffin embedded tissue sections.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenSynthetic peptide from the C-terminal domain of human Dopamine Receptor D1. The immunogen has 94% conservation with rat and 88% with mouse.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityRecognizes Dopamine Receptor D1.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
      Gene Symbol
      • DRD1
      • D
      • DRD1A
      • DADR
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P21728 # This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
      SIZE: 446 amino acids; 49293 Da
      SUBUNIT: Interacts with DNAJC14 via its C-terminus (By similarity). Interacts with DRD1IP.
      SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity). Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). Note=Transport from the endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14 (By similarity).
      TISSUE SPECIFICITY: Detected in caudate, nucleus accumbens and in the olfactory tubercle.
      SIMILARITY: SwissProt: P21728 ## Belongs to the G-protein coupled receptor 1 family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Availability by Geography
      • This product is not available for sale in Japan.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size50 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      AB9141 04053252338298

      Documentation

      Anti-Dopamine Receptor D1 Antibody MSDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Dopamine Receptor D1 Antibody Certificates of Analysis

      TitleLot Number
      RABBIT ANTI- DOPAMINE RECEPTOR D1 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2119725 2119725
      RABBIT ANTI- DOPAMINE RECEPTOR D1 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2135074 2135074
      RABBIT ANTI- DOPAMINE RECEPTOR D1 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2446677 2446677
      RABBIT ANTI- DOPAMINE RECEPTOR D1 - 4068691 4068691
      RABBIT ANTI- DOPAMINE RECEPTOR D1 -2576349 2576349
      RABBIT ANTI- DOPAMINE RECEPTOR D1 -2774139 2774139
      RABBIT ANTI- DOPAMINE RECEPTOR D1 -2776257 2776257
      RABBIT ANTI- DOPAMINE RECEPTOR D1 AFFINITY PURIFIED POLYCLONAL ANTIBODY 2990631
      RABBIT ANTI- DOPAMINE RECEPTOR D1 AFFINITY PURIFIED POLYCLONAL ANTIBODY 3098888
      RABBIT ANTI- DOPAMINE RECEPTOR D1 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 3934415 3934415

      Data Sheet

      Title
      RABBIT ANTI- DOPAMINE RECEPTOR D1

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies