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164605 Aminopeptidase N (CD13), Human Serum

164605
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164605-10UG
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      Plastic ampoule 10 μg
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      Description
      OverviewNative aminopeptidase N purified from human serum. Aminopeptidase N is a single-chain, integral membrane protease with broad specificity that functions to remove N-terminal amino acids from peptides. It also acts as a receptor for coronavirus and is known to play a role in angiogenesis, HIV entry, and in degradation of extracellular matrix as a result of tumor invasion.
      Catalogue Number164605
      Brand Family Calbiochem®
      SynonymsAPN/CD13, Aminopeptidase N
      References
      ReferencesBhagwat, S.V., et al. 2003. Blood 101, 1818.
      Kawai, M., et al. 2001. Clin. Chem. 47, 223.
      Watanabe, Y., et al. 1998. Mol. Genet. Metab. 63, 289.
      Pulido-Cejudo, G., et al. 1997. Antiviral Res. 36, 167.
      Hansen, A.S., et al. 1993. Eur. J. Immunol. 23, 2358.
      Saiki, I., et al. 1993. Int. J. Cancer 54,137.
      Shipp, M.A. and Look, A.T. 1993. Blood 82, 1052.
      Yeager, C.L., et al. 1992. Nature 357, 420.
      Product Information
      Unit of DefinitionOne unit is defined as the amount of enzyme that will hydrolyze 1.0 µmol L-leucine-p-nitroanilide) per min at 37°C, pH 7.2.
      EC number3.4.11.2
      FormLiquid
      FormulationIn 150 mM NaCl, 50 mM Tris-HCl, 1 mM CaCl₂, pH 8.0.
      Quality LevelMQ100
      Biological Information
      Purity≥92% by SDS-PAGE
      SourcePrepared from human serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Specific Activity≥450 mU/mg protein
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Global Trade Item Number
      Catalogue Number GTIN
      164605-10UG 04055977207606