Our broad portfolio consists of multiplex panels that allow you to choose, within the panel, analytes that best meet your needs. On a separate tab you can choose the premixed cytokine format or a single plex kit.
Cell Signaling Kits & MAPmates™
Choose fixed kits that allow you to explore entire pathways or processes. Or design your own kits by choosing single plex MAPmates™, following the provided guidelines.
The following MAPmates™ should not be plexed together:
-MAPmates™ that require a different assay buffer
-Phospho-specific and total MAPmate™ pairs, e.g. total GSK3β and GSK3β (Ser 9)
-PanTyr and site-specific MAPmates™, e.g. Phospho-EGF Receptor and phospho-STAT1 (Tyr701)
-More than 1 phospho-MAPmate™ for a single target (Akt, STAT3)
-GAPDH and β-Tubulin cannot be plexed with kits or MAPmates™ containing panTyr
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To begin designing your MILLIPLEX® MAP kit select a species, a panel type or kit of interest.
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48-602MAG
Buffer Detection Kit for Magnetic Beads
1 Kit
Space Saver Option Customers purchasing multiple kits may choose to save storage space by eliminating the kit packaging and receiving their multiplex assay components in plastic bags for more compact storage.
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505227
Sigma-Aldrich(-)-Cytisine - CAS 485-35-8 - Calbiochem
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Description
Overview
A potent agonist selective for neuronal nAChRs (Ki = 2, 5890, 480, 329, and 492 nM at α4β2, α7, α3β4, α6/α4β4, α1β1γδ, respectively). Clinically used as a smoking cessation medicine and often used in addiction studies.
Chen, Y., et al., 2012. Br J Pharmacol.165, 1006. West, R., 2011, N. Engl. J. Med.365, 1193. Happe, K., et al., 1994. Neurosci.62, 929. Reavill, C. et al., 1990. Neuropharmacol.29, 619.
Causes severe burns. Irritating to eyes, respiratory system and skin.
S Phrase
S: 22-26-28.1-36/37/39-46-63
Do not breathe dust. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. After contact with skin, wash immediately with plenty of water. Wear suitable protective clothing, gloves and eye/face protection. If swallowed, seek medical advice immediately and show this container or label. In case of accident by inhalation: remove casualty to fresh air and keep at rest.
Product Usage Statements
Storage and Shipping Information
Ship Code
Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity
Toxic
Hazardous Materials Attention:
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage
+2°C to +8°C
Protect from Light
Protect from light
Do not freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 3 months at -20°C.
Chen, Y., et al., 2012. Br J Pharmacol.165, 1006. West, R., 2011, N. Engl. J. Med.365, 1193. Happe, K., et al., 1994. Neurosci.62, 929. Reavill, C. et al., 1990. Neuropharmacol.29, 619.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
A potent agonist selective for neuronal nAChRs (Ki = 2, 5890, 480, 329, and 492 nM at α4β2, α7, α3β4, α6/α4β4, α1β1γδ, respectively). Clinically used as a smoking cessation medicine and often used in addiction studies.
Form
Pale yellow solid
CAS number
485-35-8
Chemical formula
C₁₁H₁₄N₂O
Structure formula
Purity
≥99% by HPLC
Solubility
H₂O (100 mM)
Storage
Protect from light
+2°C to +8°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Toxic
References
Chen, Y., et al., 2012. Br J Pharmacol.165, 1006. West, R., 2011, N. Engl. J. Med.365, 1193. Happe, K., et al., 1994. Neurosci.62, 929. Reavill, C. et al., 1990. Neuropharmacol.29, 619.
