Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

506126 p38 MAP Kinase Inhibitor - CAS 219138-24-6 - Calbiochem

The p38 MAP Kinase Inhibitor, also referenced under CAS 219138-24-6, controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1,2-dihydropyrazol-3-one

Primary Target: p38 MAP kinase
506126
  
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
219138-24-6C₂₀H₁₃ClFN₃O
Description
OverviewA potent p38 MAP kinase inhibitor (IC50 = 35 nM).
Catalogue Number506126
Brand Family Calbiochem®
Synonyms2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1,2-dihydropyrazol-3-one
References
Referencesde Laszlo, S.E., et al. 1998. Bioorg. Med. Chem. Lett. 8, 2689.
Product Information
CAS number219138-24-6
ATP CompetitiveN
FormPale yellow solid
Hill FormulaC₂₀H₁₃ClFN₃O
Chemical formulaC₂₀H₁₃ClFN₃O
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetp38 MAP kinase
Primary Target IC<sub>50</sub>35 nM
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
506126 0

Documentation

p38 MAP Kinase Inhibitor - CAS 219138-24-6 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

p38 MAP Kinase Inhibitor - CAS 219138-24-6 - Calbiochem Certificates of Analysis

TitleLot Number
506126

References

Reference overview
de Laszlo, S.E., et al. 1998. Bioorg. Med. Chem. Lett. 8, 2689.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision05-October-2007 JSW
Synonyms2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1,2-dihydropyrazol-3-one
DescriptionA potent p38 MAP kinase inhibitor (IC50 = 35 nM).
FormPale yellow solid
Intert gas (Yes/No) Packaged under inert gas
CAS number219138-24-6
Chemical formulaC₂₀H₁₃ClFN₃O
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (25 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
Referencesde Laszlo, S.E., et al. 1998. Bioorg. Med. Chem. Lett. 8, 2689.