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14-732M VRK2, active

VRK2, active MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
14-732M
250 µg  Also available in 10μg size as catalog # 14-732 and in 250 μg as catalog # 14-732M.
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue Number14-732M
Trade Name
  • Upstate
DescriptionVRK2, active
OverviewVRK2 is a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This protein
is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis,
leukocytes, fetal liver, and carcinomas. Its protein localizes to the endoplasmic reticulum and has been shown to
phosphorylate casein and undergo autophosphorylation. Multiple alternatively spliced transcript variants have been
found for this gene.
References
Product Information
PresentationProtein in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Quality LevelMQ100
Applications
Key Applications
  • Kinase Assay
Biological Information
SourceN-terminal 6His-tagged, recombinant, human VRK2 amino acids 1–336, expressed by baculovirus in Sf21 insect cells
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Gene Symbol
  • VRK2
Purification MethodPurified using Ni2+/NTA agarose.
Target Sub-FamilyCK1
UniProt Number
Molecular Weight43 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by phosphorylation of casein
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C
Packaging Information
Material Size250 µg
Material PackageAlso available in 10μg size as catalog # 14-732 and in 250 μg as catalog # 14-732M.
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
14-732M 04053252411861

Related Products & Applications

Alternative Packsize

Catalogue Number Description
14-732 VRK2, active

Product Families

Kinase & Phosphatase Products

Millipore offers a large portfolio of Kinases, Phophatases, Substrates, Inhibitors, Kits, reagents & tools for Signaling research. See below for a list of these products, in multiple pack sizes.
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Categories

Life Science Research > Proteins and Enzymes > Purified Kinases
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases