567790 Sigma-AldrichST638
A cell-permeable, reversible, and substrate competitive protein tyrosine kinase inhibitor (IC₅₀ = 370 nM) that also inhibits HGF-induced MAP kinase activation in hepatocytes.
More>> A cell-permeable, reversible, and substrate competitive protein tyrosine kinase inhibitor (IC₅₀ = 370 nM) that also inhibits HGF-induced MAP kinase activation in hepatocytes. Less<<ST638 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: α-Cyano-(3-ethoxy-4-hydroxy-5-phenylthiomethyl)cinnamide
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Overview
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Key Spec Table
| CAS # | Empirical Formula |
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| 107761-24-0 | C₁₉H₁₈N₂O₃S |
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| CAS number | 107761-24-0 |
| ATP Competitive | Y |
| Form | Pale yellow solid |
| Hill Formula | C₁₉H₁₈N₂O₃S |
| Chemical formula | C₁₉H₁₈N₂O₃S |
| Reversible | Y |
| Structure formula Image | |
| Applications |
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| Biological Information | |
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| Primary Target | protein tyrosine kinase |
| Primary Target IC<sub>50</sub> | 370 nM against protein tyrosine kinase |
| Purity | ≥98% by HPLC |
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| Cell permeable | Y |
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| RTECS | UC6316200 |
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| Specifications |
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| Global Trade Item Number | |
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| Catalogue Number | GTIN |
| 567790 | 0 |
Documentation
ST638 SDS
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ST638 Certificates of Analysis
| Title | Lot Number |
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| 567790 |
References
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| Adachi, T., et al. 1996. Hepatology 23, 1244. Yamaguchi, M., et al. 1995. Arch. Biochem. Biophys. 323, 382. Uings, I., et al. 1992. Biochem. J. 281, 597. Shiraishi, T., et al. 1988. Chem. Pharm. Bull. 36, 974. |