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505626 (S)-Sulpiride - CAS 23672-07-3 - Calbiochem

(S)-Sulpiride - CAS 23672-07-3 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (S)-(-)-5-Aminosulfonyl-N-[(1-ethyl­-2-pyrrolidinyl)methyl]-2-methoxybenzamide, D2-like dopamine antagonist, (s)-Sulpiride, Sulpiride

Primary Target: D2-like dopamine receptors
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
23672-07-3C₁₅H₂₃N₃O₄S
Description
Overview

This product has been discontinued.



Dopamine D2 receptor antagonist with good aqueous solubility. S-sulpiride (200 nm) was used to confirm that dopamine currents were mediated through the D2 receptor in whole animal rat brain preps. IC50 of 0.01012 µM Antagonist activity at human dopamine D2 receptor expressed in CHOp cells assessed as inhibition of quinopirole-induced mitogenisis.
Catalogue Number505626
Brand Family Calbiochem®
Synonyms(S)-(-)-5-Aminosulfonyl-N-[(1-ethyl­-2-pyrrolidinyl)methyl]-2-methoxybenzamide, D2-like dopamine antagonist, (s)-Sulpiride, Sulpiride
References
ReferencesEagle, D. M. et al. 2011. J. Neurosci. 31, 7349.
Banala, A. K. et al. 2011. J. Med. Chem. 54, 3581.
Seeman, P. and Van Tol, H. H. 1994. Trends Pharmacol. Sci. 15, 264.
Product Information
CAS number23672-07-3
FormWhite solid
Hill FormulaC₁₅H₂₃N₃O₄S
Chemical formulaC₁₅H₂₃N₃O₄S
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetD2-like dopamine receptors
Purity≥99% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
505626 0

Documentation

(S)-Sulpiride - CAS 23672-07-3 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
Eagle, D. M. et al. 2011. J. Neurosci. 31, 7349.
Banala, A. K. et al. 2011. J. Med. Chem. 54, 3581.
Seeman, P. and Van Tol, H. H. 1994. Trends Pharmacol. Sci. 15, 264.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision12-September-2013 JSW
Synonyms(S)-(-)-5-Aminosulfonyl-N-[(1-ethyl­-2-pyrrolidinyl)methyl]-2-methoxybenzamide, D2-like dopamine antagonist, (s)-Sulpiride, Sulpiride
DescriptionDopamine D2 receptor antagonist with good aqueous solubility. S-sulpiride (200 nm) was used to confirm that dopamine currents were mediated through the D2 receptor in whole animal rat brain preps. IC50 of 0.01012 µM Antagonist activity at human dopamine D2 receptor expressed in CHOp cells assessed as inhibition of quinopirole-induced mitogenisis.
FormWhite solid
CAS number23672-07-3
Chemical formulaC₁₅H₂₃N₃O₄S
Structure formulaStructure formula
Purity≥99% by HPLC
SolubilityDMSO (100 mM)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesEagle, D. M. et al. 2011. J. Neurosci. 31, 7349.
Banala, A. K. et al. 2011. J. Med. Chem. 54, 3581.
Seeman, P. and Van Tol, H. H. 1994. Trends Pharmacol. Sci. 15, 264.