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504840 (R)-CPPene - CAS 117414-74-1 - Calbiochem

(R)-CPPene - CAS 117414-74-1 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (R)-4-[(2E)-3-Phosphono-2-propenyl]-2-piperazinecarboxylic acid, SDZ EAA 494, Midafotel

Primary Target: NMDA receptors
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
117414-74-1C₈H₁₅N₂O₅P
Description
Overview

This product has been discontinued.



A highly potent competitive antagonist of NMDA receptors (ED50 = 39 nM; pA2 = 6.8). Biologically active admitted systemically. Frequently used in assessing the functional roles of NMDA receptors mediated neurotransmissions in a variety of research areas, such as excitotoxic cell death, apoptosis, bipolar disorders, ischemia, traumatic brain injury, epilepsy, and neuropathic pain.
Catalogue Number504840
Brand Family Calbiochem®
Synonyms(R)-4-[(2E)-3-Phosphono-2-propenyl]-2-piperazinecarboxylic acid, SDZ EAA 494, Midafotel
References
ReferencesLowe, D., et al. 1990. Neurosci. Lett. 113, 315.
Bullock, R., et al. 1990. Stroke. 21, 32.
Bespalov, A., et al. 1998. Eur. J. Pharmacol. 351, 299.
Lowe, D., et al. 1994. Neurochem. Inter. 25, 583.
Duty, S. 2012. CNS Drugs 26, 1017.
Product Information
CAS number117414-74-1
FormWhite solid
Hill FormulaC₈H₁₅N₂O₅P
Chemical formulaC₈H₁₅N₂O₅P
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetNMDA receptors
Purity≥99% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
504840 0

Documentation

(R)-CPPene - CAS 117414-74-1 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
Lowe, D., et al. 1990. Neurosci. Lett. 113, 315.
Bullock, R., et al. 1990. Stroke. 21, 32.
Bespalov, A., et al. 1998. Eur. J. Pharmacol. 351, 299.
Lowe, D., et al. 1994. Neurochem. Inter. 25, 583.
Duty, S. 2012. CNS Drugs 26, 1017.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision26-July-2013 JSW
Synonyms(R)-4-[(2E)-3-Phosphono-2-propenyl]-2-piperazinecarboxylic acid, SDZ EAA 494, Midafotel
DescriptionA highly potent competitive antagonist of NMDA receptors (ED50 = 39 nM; pA2 = 6.8). Biologically active admitted systemically. Frequently used in assessing the functional roles of NMDA receptors mediated neurotransmissions in a variety of research areas, such as excitotoxic cell death, apoptosis, bipolar disorders, ischemia, traumatic brain injury, epilepsy, and neuropathic pain.
FormWhite solid
CAS number117414-74-1
Chemical formulaC₈H₁₅N₂O₅P
Structure formulaStructure formula
Purity≥99% by HPLC
SolubilityH₂O (100 mM)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesLowe, D., et al. 1990. Neurosci. Lett. 113, 315.
Bullock, R., et al. 1990. Stroke. 21, 32.
Bespalov, A., et al. 1998. Eur. J. Pharmacol. 351, 299.
Lowe, D., et al. 1994. Neurochem. Inter. 25, 583.
Duty, S. 2012. CNS Drugs 26, 1017.