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524731 Phosphodiesterase 4A4, His•Tag®, Human, Recombinant, S. frugiperda

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: PDE4A4, cAMP-specific phosphodiesterase 4A isoform 4

524731
  
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Overview

Replacement Information
Description
OverviewFull-length, recombinant, human phosphodiesterase 4A4 (accession no. L20965) fused at the N-terminus to a His•Tag® sequence and expressed in S. frugiperda insect cells using a baculovirus expression system. Supplied as a partially purified, catalytically active preparation.
Catalogue Number524731
Brand Family Calbiochem®
SynonymsPDE4A4, cAMP-specific phosphodiesterase 4A isoform 4
Application Data
Phosphodiesterase 4A4 was treated with increasing concentrations of the inhibitor Rolipram (Cat. No. 557330) and activity determined. The IC50 is 1.3 µM.
References
ReferencesGibson, L.C.D., et al. 2006. Eur. J. Pharmacol. 538, 39.
Xu, R.X., et al. 2000. Science 288, 1822.
Product Information
Activity≥0.5 units/µl
Unit of DefinitionOne unit is defined as the amount of enzyme that will convert 1 pmole cAMP to AMP per min at 30°C, pH 7.5.
FormLiquid
FormulationIn 150 mM NaCl, 10 mM Tris-HCl, pH 8.3.
Quality LevelMQ100
Applications
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
524731 0

Documentation

Phosphodiesterase 4A4, His•Tag®, Human, Recombinant, S. frugiperda SDS

Title

Safety Data Sheet (SDS) 

Phosphodiesterase 4A4, His•Tag®, Human, Recombinant, S. frugiperda Certificates of Analysis

TitleLot Number
524731

References

Reference overview
Gibson, L.C.D., et al. 2006. Eur. J. Pharmacol. 538, 39.
Xu, R.X., et al. 2000. Science 288, 1822.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision03-February-2009 JSW
SynonymsPDE4A4, cAMP-specific phosphodiesterase 4A isoform 4
Application Data
Phosphodiesterase 4A4 was treated with increasing concentrations of the inhibitor Rolipram (Cat. No. 557330) and activity determined. The IC50 is 1.3 µM.
DescriptionFull-length, recombinant, human phosphodiesterase 4A4 (accession no. L20965) fused at the N-terminuse to a His•Tag® sequence and expressed in S. frugiperda insect cells using a baculovirus expression system. Supplied as a partially purified, catalytically active preparation.
FormLiquid
FormulationIn 150 mM NaCl, 10 mM Tris-HCl, pH 8.3.
Activity≥0.5 units/µl
Unit definitionOne unit is defined as the amount of enzyme that will convert 1 pmole cAMP to AMP per min at 30°C, pH 7.5.
Storage Avoid freeze/thaw
≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Toxicity Standard Handling
ReferencesGibson, L.C.D., et al. 2006. Eur. J. Pharmacol. 538, 39.
Xu, R.X., et al. 2000. Science 288, 1822.