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539510 PP2A₂, Bovine Kidney

PP2A₂, Bovine Kidney MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Protein Phosphatase 2A₂

539510
  
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Overview

Description
OverviewNative, PP2A2 from bovine kidney. A divalent cation-independent protein serine/threonine phosphatase involved in the control of numerous cellular processes. Has a catalytic subunit of 36 kDa and a regulatory subunit of 60 kDa. Transient phosphorylation of the catalytic subunit on threonine or tyrosine residues has been reported to inactivate PP2A2. Inhibits nuclear telomerase activity in human breast cancer cells.

This product has been discontinued.
Catalogue Number539510
Brand Family Calbiochem®
SynonymsProtein Phosphatase 2A₂
References
ReferencesLi, H., et al. 1997. J. Biol. Chem. 272, 16729.
Guo, H. and Damuni, Z. 1993. Proc. Natl. Acad. Sci. USA 90, 2500.
Hendrix, P., et al. 1993. J. Biol. Chem. 268, 15267.
Amick, G.D., et al. 1992. Biochem. J. 287, 1019.
Chen, J., et al. 1992. Science 257, 1261.
Cohen, P., et al. 1990. Trends Biochem. Sci. 15, 98.
Damuni, Z., et al. 1989. J. Biol. Chem. 264, 6412.
Product Information
Unit of DefinitionOne unit is defined as the amount of enzyme that will release 1.0 nmol of [³²P]P<sub>i</sub> from ³²P-labeled phosphorylase per min at 30°C, pH 7.0.
EC number3.1.3.16
FormLiquid
FormulationIn 25 mM Tris-HCl, 14 mM βME, 1 mM benzamidine, 100 µM EDTA, 100 µM PMSF, 50% glycerol, pH 7.0.
Biological Information
Purity≥90% by SDS-PAGE
Specific Activity≥750 units/mg
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Global Trade Item Number
Catalogue Number GTIN
539510 0