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505316 PHA-543,613 - CAS 478149-53-0 - Calbiochem

PHA-543,613 - CAS 478149-53-0 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, Alpha 7 Nicotinic Acetylcholine Receptor (α7 nAChR) Agonist, PHA-543613

Primary Target: α7 nAChR
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
478149-53-0C₁₅H₁₇N₃O₂
Description
Overview

This product has been discontinued.



A potent agonist highly selective for α7 nicotinic acetylcholine receptor (α7 nAChR). Bioavaible admitted orally. Widely used in studies of the functional roles of α7 nAChR in learning and memory, sensory gating, and cognitive functions as well as Schizophrenia and Alzheimer′s disease.
Catalogue Number505316
Brand Family Calbiochem®
SynonymsN-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, Alpha 7 Nicotinic Acetylcholine Receptor (α7 nAChR) Agonist, PHA-543613
References
ReferencesMazurov, A., et al., 2011. J. Med. Chem. 54, 7943.
Wishka, G., et al., 2006. J. Med. Chem. 49, 4425.
Faghih, R., et al., 2008. J. Med. Chem. 51, 701.
Product Information
CAS number478149-53-0
FormWhite powder
Hill FormulaC₁₅H₁₇N₃O₂
Chemical formulaC₁₅H₁₇N₃O₂
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetα7 nAChR
Purity≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
505316 0

Documentation

PHA-543,613 - CAS 478149-53-0 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
Mazurov, A., et al., 2011. J. Med. Chem. 54, 7943.
Wishka, G., et al., 2006. J. Med. Chem. 49, 4425.
Faghih, R., et al., 2008. J. Med. Chem. 51, 701.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision17-July-2013 JSW
SynonymsN-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, Alpha 7 Nicotinic Acetylcholine Receptor (α7 nAChR) Agonist, PHA-543613
DescriptionA potent agonist highly selective for α7 nicotinic acetylcholine receptor (α7 nAChR). Bioavaible admitted orally. Widely used in studies of the functional roles of α7 nAChR in learning and memory, sensory gating, and cognitive functions as well as Schizophrenia and Alzheimer′s disease.
FormWhite powder
CAS number478149-53-0
Chemical formulaC₁₅H₁₇N₃O₂
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityDMSO (20 mg/ml)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesMazurov, A., et al., 2011. J. Med. Chem. 54, 7943.
Wishka, G., et al., 2006. J. Med. Chem. 49, 4425.
Faghih, R., et al., 2008. J. Med. Chem. 51, 701.