479830 Sigma-AldrichNBI-31772 - CAS 374620-70-9 - Calbiochem
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Primary Target:
Human insulin-like growth factor-I binding proteins (IGFBPs).
NBI-31772 - CAS 374620-70-9 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: [1-(3ʹ,4ʹ-Dihydroxybenzoyl)-6,7-dihydroxyisoquinoline-3-carboxylic Acid]
Recommended Products
Overview
| Replacement Information |
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Key Spec Table
| CAS # | Empirical Formula |
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| 374620-70-9 | C₁₇H₁₁NO₇ |
| Description | |
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| Overview | This product has been discontinued. We are offering NBI 31772 hydrate (Cat. No. N8289) as a possible alternative. Please read the alternative product documentation carefully and contact technical service if you need additional information. A non-peptide ligand that exhibits high-affinity (Ki ~ 1 - 17 nM) towards all six human insulin-like growth factor-I binding proteins (IGFBPs). Displaces insulin-like growth factor-I (IGF-I) from the IGF-I:IGFBP complex in 3T3 fibroblasts; however, it does not interact with the IGF receptors. |
| Catalogue Number | 479830 |
| Brand Family | Calbiochem® |
| Synonyms | [1-(3ʹ,4ʹ-Dihydroxybenzoyl)-6,7-dihydroxyisoquinoline-3-carboxylic Acid] |
| References | |
|---|---|
| References | Chen, C., et al. 2001. J. Med. Chem. 44, 4001. Liu, X.J., et al. 2001. J. Biol. Chem. 276, 32419. |
| Product Information | |
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| CAS number | 374620-70-9 |
| ATP Competitive | N |
| Form | Greenish-yellow solid |
| Hill Formula | C₁₇H₁₁NO₇ |
| Chemical formula | C₁₇H₁₁NO₇ |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | Human insulin-like growth factor-I binding proteins (IGFBPs). |
| Purity | ≥95% by HPLC |
| Physicochemical Information | |
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| Cell permeable | N |
| Dimensions |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information |
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| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
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| Catalogue Number | GTIN |
| 479830 | 0 |
Documentation
NBI-31772 - CAS 374620-70-9 - Calbiochem SDS
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NBI-31772 - CAS 374620-70-9 - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 479830 |
References
| Reference overview |
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| Chen, C., et al. 2001. J. Med. Chem. 44, 4001. Liu, X.J., et al. 2001. J. Biol. Chem. 276, 32419. |