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420321 KT5823 - CAS 126643-37-6 - Calbiochem

Highly specific, cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase G (Ki = 234 nM).

KT5823 - CAS 126643-37-6 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: PKG Inhibitor VII

Primary Target: PKG
420321
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
126643-37-6C₂₉H₂₅N₃O₅

Products

Catalogue NumberPackaging Qty/Pack
420321-100UG Plastic ampoule 100 μg
420321-50UG Plastic ampoule 50 μg
Description
OverviewHighly specific, cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase G (Ki = 234 nM).
Catalogue Number420321
Brand Family Calbiochem®
SynonymsPKG Inhibitor VII
References
ReferencesGrider, J.R. 1993. Am. J. Physiol. 264, G334.
Product Information
CAS number126643-37-6
ATP CompetitiveY
FormWhite solid
Hill FormulaC₂₉H₂₅N₃O₅
Chemical formulaC₂₉H₂₅N₃O₅
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetPKG
Primary Target K<sub>i</sub>234 nM against protein kinase G
Purity≥98% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
420321-100UG 04055977211047
420321-50UG 04055977211054

Documentation

KT5823 - CAS 126643-37-6 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

KT5823 - CAS 126643-37-6 - Calbiochem Certificates of Analysis

TitleLot Number
420321

References

Reference overview
Grider, J.R. 1993. Am. J. Physiol. 264, G334.

Citations

Title
  • Mike T. Lin, et al. (2005) Ca2+-activated K+ channel-associated phosphatase and kinase activities during development. American Journal of Physiology Heart and Circulatory Physiology 289, H414-H425.
  • Bing Zhu, Samuel Strada and Troy Stevens. (2005) Cyclic GMP-specific phosphodiesterase 5 regulates growth and apoptosis in pulmonary endothelial cells. American Journal of Physiology Lung Cellular and Molecular Physiology 289, L196-L206.
    		•
    Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision30-July-2008 RFH
    SynonymsPKG Inhibitor VII
    DescriptionHighly specific cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase G (Ki = 234 nM). Inhibits protein kinase C (Ki = 4.0 µM) and protein kinase A (Ki > 10.0 µM) at higher concentrations.
    FormWhite solid
    CAS number126643-37-6
    Chemical formulaC₂₉H₂₅N₃O₅
    Structure formulaStructure formula
    Purity≥98% by HPLC
    SolubilityDMF or DMSO (1 mg/ml). Further dilute with aqueous buffers just prior to use.
    Storage Protect from light
    -20°C
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    Toxicity Standard Handling
    ReferencesGrider, J.R. 1993. Am. J. Physiol. 264, G334.
    Citation
  • Mike T. Lin, et al. (2005) Ca2+-activated K+ channel-associated phosphatase and kinase activities during development. American Journal of Physiology Heart and Circulatory Physiology 289, H414-H425.
  • Bing Zhu, Samuel Strada and Troy Stevens. (2005) Cyclic GMP-specific phosphodiesterase 5 regulates growth and apoptosis in pulmonary endothelial cells. American Journal of Physiology Lung Cellular and Molecular Physiology 289, L196-L206.
    		•