407950 Sigma-AldrichIonomycin, Free Acid, Streptomyces conglobatus - CAS 56092-81-0 - Calbiochem
Ionomycin, Free Acid, Streptomyces conglobatus, CAS 56092-81-0, is an ionophore with high specificity for divalent cations. More effective than A23187 as a mobile ion carrier for Ca2+.
More>> Ionomycin, Free Acid, Streptomyces conglobatus, CAS 56092-81-0, is an ionophore with high specificity for divalent cations. More effective than A23187 as a mobile ion carrier for Ca2+. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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Overview
| Replacement Information |
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Key Spec Table
| CAS # | Empirical Formula |
|---|---|
| 56092-81-0 | C₄₁H₇₂O₉ |
Products
| Catalogue Number | Packaging | Qty/Pack | |
|---|---|---|---|
| 407950-10MG | Plastic ampoule | 10 mg | |
| 407950-1MG | Plastic ampoule | 1 mg | |
| 407950-5MG | Plastic ampoule | 5 mg |
| Description | |
|---|---|
| Overview | Highly specific for divalent cations and more effective than A23187 (Cat. No. 100105) as a mobile ion carrier for Ca2+. Complexes with Ca2+ between pH 7 and 9.5. In contrast to A23187, it is not fluorescent. Useful for studies of Ca2+ transport across biological membranes and measurement of cytoplasmic free Ca2+. Induces apoptotic neuronal degeneration in embryonic cortical neurons and cell cycle arrest in the G1 phase in mature Burkitt lymphoma cell lines. |
| Absorption max. (280 nm, MeOH): 18,600 M-1cm-1. | |
| Catalogue Number | 407950 |
| Brand Family | Calbiochem® |
| Product Information | |
|---|---|
| CAS number | 56092-81-0 |
| ATP Competitive | N |
| Form | Waxy solid |
| Hill Formula | C₄₁H₇₂O₉ |
| Chemical formula | C₄₁H₇₂O₉ |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Biological Information | |
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| Primary Target | Mobile ion carrier for Ca2+ |
| Purity | ≥90% by HPLC |
| Physicochemical Information | |
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| Cell permeable | N |
| Dimensions |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS | |
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| RTECS | NO0600000 |
| Safety Information | |
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| R Phrase | R: 22 Harmful if swallowed. |
| S Phrase | S: 36 Wear suitable protective clothing. |
| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
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| Catalogue Number | GTIN |
| 407950-10MG | 04055977211566 |
| 407950-1MG | 04055977211559 |
| 407950-5MG | 04055977211573 |
Documentation
Ionomycin, Free Acid, Streptomyces conglobatus - CAS 56092-81-0 - Calbiochem SDS
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Ionomycin, Free Acid, Streptomyces conglobatus - CAS 56092-81-0 - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 407950 |
References
| Reference overview |
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| Aagaard-Tillery, K.M., and Jelinek, D.F. 1995. J. Immunol. 155, 3297. Takei, N., and Endo, Y. 1994. Brain Res. 652, 65. Dupuy d’Angeac, A., et al. 1993. J. Cell Physiol. 154, 44. Lee, H.C. 1993. J. Biol. Chem. 268, 293. Kuznetsov, G., et al. 1992. J. Biol. Chem. 267, 3932. Toeplitz, B.K., et al. 1979. J. Am. Chem. Soc. 101, 3344. Liu, C.M., and Hermann, T.E. 1978. J. Biol. Chem. 253, 5892. |
Brochure
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| Caspases and other Apoptosis Related Tools Brochure |
Citations
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