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565784 InSolution™ γ-Secretase Inhibitor IX - Calbiochem

InSolution™ g-Secretase Inhibitor IX, CAS 208255-80-5, is a 25 mM (5 mg/462 µl or 10 mg/924 µl) solution of g-secretase Inhibitor IX (DAPT; Cat. No. 565770) in DMSO.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-Butyl Ester, DAPT

Primary Target: Aβtotal
565784
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Overview

Key Spec Table

Empirical Formula
C₂₃H₂₆F₂N₂O₄

Products

Catalogue NumberPackaging Qty/Pack
565784-10MG Plastic ampoule 10 mg
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565784-5MG Glass bottle 5 mg
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Description
Catalogue Number565784
Brand Family Calbiochem®
SynonymsN-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-Butyl Ester, DAPT
References
ReferencesOddo, S., et al. 2004. Neuron 43, 321.
Dovey, H.F., et al. 2001. J. Neurochem. 76, 173.
Vandermeeren, M., et al. 2001. Neurosci. Lett. 315, 145.
Product Information
ATP CompetitiveN
FormClear colorless liquid
FormulationA 25 mM (5 mg/462 µl or 10 mg/924 µl) solution of γ-Secretase Inhibitor IX (Cat. No. 565770) in DMSO.
Hill FormulaC₂₃H₂₆F₂N₂O₄
Chemical formulaC₂₃H₂₆F₂N₂O₄
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary TargetAβtotal
Primary Target IC<sub>50</sub>115 nM, 200 nM against Aβtotal, Aβ42, respectively
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Storage and Shipping Information
Ship Code Shipped with Blue Ice or with Dry Ice
Toxicity Irritant
Storage +2°C to +8°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing initial use, aliquot and freeze (-20°C).
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Catalogue Number GTIN
565784-10MG 04055977267303
565784-5MG 04055977191806