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500111 Cocarboxylase tetrahydrate

(thiamine diphosphoric acid ester tetrahydrate) EMPROVE® API

Cocarboxylase tetrahydrate MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 68684-55-9 EC Number: 205-230-7 Molar Mass: 496.37 g/mol Hill Formula: C₁₂H₁₈N₄O₇P₂S * 4 H₂O
500111
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Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaMolar Mass
68684-55-9205-230-7C₁₂H₁₈N₄O₇P₂S * 4 H₂O496.37 g/mol

Products

Catalogue NumberPackaging Qty/Pack
5001110100 Plastic bottle 100 g
5001115000 Plastic bottle 5 kg
Description
Catalogue Number500111
References
Product Information
CAS number68684-55-9
EC number205-230-7
Hill FormulaC₁₂H₁₈N₄O₇P₂S * 4 H₂O
Molar Mass496.37 g/mol
HS Code2936 22 00
Structure formula ImageStructure formula Image
Quality LevelMQ600
Applications
Biological Information
Physicochemical Information
pH value2.4 - 3.2 (100 g/l, H₂O, 20 °C)
Bulk density450 kg/m3
Solubility55 g/l
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +25°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Assay (HPLC, calc.on anhydrous substance)96.0 - 101.0 %
Identity (IR-spectrum)passes test
pH-value (10 %; water)2.4 - 3.2
Chloride (Cl) (Ion Chromatography)≤ 0.025 %
Free phosphate (PO₄)≤ 1.0 %
Al (Aluminium)≤ 0.0010 %
Ni (Nickel)*≤ 0.0002 %
Dithiamine Diphosphate (HPLC)≤ 0.10 %
Dithiamine Triphosphate (HPLC)≤ 0.2 %
Thiamine & Dithiamine Phosphate (as Thiamine) (HPLC)≤ 0.1 %
Thiamine Phosphate (HPLC)≤ 1.5 %
Thiamine Triphosphate (HPLC)≤ 0.5 %
Largest unspecified impurity (HPLC)≤ 0.10 %
Sum of unspecified impurities (HPLC)≤ 0.3 %
Residual Solvents of class 3 ((2-Propanol) according to ICH Q3C)≤ 0.2 %
Other residual solvents (according to ICH Q3C)excluded by manufacturing process
Water14.0 - 16.5 %
E.coliIn 1g substance not detectable
Endotoxins< 12
Colony count (aerobic bacteria (TAMC))≤ 1000 CFU/g
Colony count (Yeasts and moulds (TYMC))≤ 100 CFU/g
Microbiological testpasses test
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities).
Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Global Trade Item Number
Catalogue Number GTIN
5001110100 04027269394547
5001115000 04022536255910

Documentation

Emprove® API Information Package

Title

Cocarboxylase tetrahydrate SDS

Title

Safety Data Sheet (SDS) 

Cocarboxylase tetrahydrate Certificates of Analysis

Product Number PackagingSpecificationLot Number
5001110100 Plastic bottlePDF Specification Document
5001115000 Plastic bottlePDF Specification Document

Certificates

Title

Brochure

Title
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