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CC170 Bone dECM Gel Hydrogel Kit

Bone decellularized ECM scaffold for traditional 2D and 3D cell culture applications.

CC170
1 Kit  
Purchase on Sigma-Aldrich

Overview

Description
Catalogue NumberCC170
DescriptionBone dECM Gel Hydrogel Kit
OverviewThe cellular microenvironment directly and indirectly effects cellular behavior via both biophysical and biochemical routes. The microenvironment is composed of extracellular matrix proteins (ECM), other surrounding cells, cytokines, growth factors, hormones, and other bioactive agents and nano/microscale mechanical properties such as physical tension/stiffness. Decellularization is the process used in biomedical engineering to isolate the native extracellular matrix (ECM) of a tissue from its inhabiting cells, leaving an ECM scaffold of the original tissue, which can be used in cell culture and tissue regeneration. Compared to other tumor derived basement membrane extracts (Matrigel@), these dECM hydrogel scaffolds can provide a more physiological environment with increased growth rates for cells without the use of any exogenous growth factors. Our tissue-specific dECM Gel Hydrogel Kits are a series of native decellularized extracellular matrix (ECM) protein solutions derived from a variety of non-diseased porcine organs (bone, heart, liver, kidney, intestine, skin and lung). These hydrogels can be used as traditional 2D ECM coatings or as hydrogels to encapsulate cells for 3D cell culture applications.
Alternate Names
  • Decellularized Extracellular Matrix Scaffold
Product Information
Components
  • Bone ECM Solution (CS226429): 2 ea (0.3 mL)
  • Component A (CS226431): 1 ea (1 mL)
  • Component B (CS226430): 1 ea (1 mL)
Applications
ApplicationBone decellularized ECM scaffold for traditional 2D and 3D cell culture applications.
Key Applications
  • Cell Culture
Biological Information
HostPorcine
Product Usage Statements
Quality AssurancepH: 2.0-3.0
Gelation: Forms Gel
Biocompatibility: > 90% Cell Viability
Sterility: No Fungi or Bacteria Detected
Mycoplasma: Negative
PRRS, PRV: Negative
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore all components of the dECM Gel Hydrogel Kit at 2-8°C (do not freeze).
Packaging Information
Material Size1 Kit
Global Trade Item Number
Catalogue Number GTIN
CC170 04065265237505