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MABF276 Anti-S100A9/MRP14 Antibody, clone 17

This Anti-S100A9/MRP14 Antibody, clone 17 is validated for use in Western Blotting and Flow Cytometry for the detection of S100A9/MRP14.

Anti-S100A9/MRP14 Antibody, clone 17 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: S100A9, CAGB, CFAG, MRP14 UniProt Number: P06702
MABF276
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, FCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABF276
DescriptionAnti-S100A9/MRP14 Antibody, clone 17
Alternate Names
  • Protein S100-A9
  • Calgranulin-B
  • Calprotectin L1H subunit
  • Leukocyte L1 complex heavy chain
  • Migration inhibitory factor-related protein 14
  • MRP-14
  • p14
  • S100 calcium-binding protein A9
Background InformationS100A8, also known as Protein S100-A8, Calgranulin-A, Calprotectin L1L subunit, Cystic fibrosis antigen (CFAG), Leukocyte L1 complex light chain, Migration inhibitory factor related protein 8 (MRP-14), p8, S100 calcium binding protein A8, or Urinary stone protein band A, and encoded by the gene S100A8/CAGA/CFAG/MRP14, is an important protein that binds both zinc and calcium and plays an important role in the regulation of inflammatory processes and immune response. Found in complex with its partner S100A9, S100A8 facilitates chemotaxis, fatty acid trafficking, cytoskeleton reorganization, and NAPDPH oxidase activation and other intracellular activities, as well as a host of extracellular induced activities such as extracellular proinflammatory, antimicrobial, oxidant scavenging, and apoptotic activities . Additionally S100A8 can act as a potent autoimmunity amplifier and appears to augment various cancers and their spread when over expressed. S100A8 is widely expressed and used as biomarker in patients with inflammatory diseases and as a cancer marker in multiple forms of cancer.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-S100A9/MRP14 Antibody, clone 17 is validated for use in Western Blotting and Flow Cytometry for the detection of S100A9/MRP14.
Key Applications
  • Western Blotting
  • Flow Cytometry
Application NotesFlow Cytometry Analysis: 0.5 µg of this antibody from a representative lot detected S100A9/MRP14 in 1X10E6 peripheral blood mononuclear cells.
Biological Information
ImmunogenRecombinant protein corresponding to human S100A9/MRP14.
Clone17
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • S100A9
  • CAGB
  • CFAG
  • MRP14
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~13 kDa observed. Uncharacterized bands may be observed in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human spleen tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected S100A9/MRP14 in 10 µg of human spleen tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABF276 04055977112115