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MABN476 Anti-Paris/ZNF746 Antibody, clone N196/16

Anti-Paris/ZNF746 Antibody, clone N196/16 is a highly specific mouse monoclonal antibody & that targets Zinc Finger Protein & has been tested in western blotting.

Anti-Paris/ZNF746 Antibody, clone N196/16 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Neurodegenerative Diseases Gene Symbol: ZNF746, PARIS UniProt Number: Q6NUN9
MABN476
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, RWBMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABN476
DescriptionAnti-Paris/ZNF746 Antibody, clone N196/16
Alternate Names
  • Zinc finger protein 746
  • Parkin-interacting substrate
  • PARIS
Background InformationZinc finger protein 746 (ZNF746) is also called Parkin-interacting substrate (PARIS). ZNF746 is a repressor of transcription that binds to promoters and represses the transcription of PGC-1-alpha (PPARGC1A), making it important to the regulation of neuron death. ZNF746 may also contribute to neurodegeneration in Parkinson disease.
References
Product Information
FormatPurified
Control
  • HEK293 cell lysate
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Paris/ZNF746 Antibody, clone N196/16 is a highly specific mouse monoclonal antibody & that targets Zinc Finger Protein & has been tested in western blotting.
Key Applications
  • Western Blotting
Application NotesWestern Blotting Analysis: 1 µg/mL of this antibody detected Paris/ZNF746 in 10 µg of RAW264.7 cell lysate. Immunohistochemistry Analysis: A representative lot detected Paris/ZNF746 in rat brain tissue (Prof. J. Trimmer, University of California, Davis.).
Biological Information
ImmunogenRecombinant protein corresponding to the N-terminus of human Paris/ZNF746.
EpitopeN-terminus
CloneN196/16
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityThis antibody recognizes the N-terminus of ZNF746. This antibody does not cross react with ZNF783 or ZNF398 (Prof. J. Trimmer, University of California, Davis.).
IsotypeIgG1κ
Species Reactivity
  • Human
  • Mouse
  • Rat
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • ZNF746
  • PARIS
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~72 kDa observed. Uniprot describes 3 isoforms, two at 69 kDa and one at 49 kDa. This protein is ubiquitinated and has been observed at higher molecular weights (Shin, J. H., et al. (2011). Cell. 144(5):689-702.).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in HEK293 cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected Paris/ZNF746 in 10 µg of HEK293 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABN476 04053252912443

Documentation

Anti-Paris/ZNF746 Antibody, clone N196/16 SDS

Title

Safety Data Sheet (SDS) 

Anti-Paris/ZNF746 Antibody, clone N196/16 Certificates of Analysis

TitleLot Number
Anti-Paris/ZNF746 clone N196/16 - 3251023 3251023
Anti-Paris/ZNF746 clone N196/16 - 3462123 3462123
Anti-Paris/ZNF746 clone N196/16 - 3521077 3521077
Anti-Paris/ZNF746 clone N196/16 - 3698723 3698723
Anti-Paris/ZNF746 clone N196/16 - 3831722 3831722
Anti-Paris/ZNF746 clone N196/16 - 3988531 3988531
Anti-Paris/ZNF746 clone N196/16 - 4138112 4138112
Anti-Paris/ZNF746 clone N196/16 - 4158362 4158362
Anti-Paris/ZNF746 clone N196/16 - Q2204790 Q2204790
Anti-Paris/ZNF746 clone N196/16 -2809944 2809944
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