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MABS1214 Anti-PEG (methoxy group) Antibody, clone RM105

Anti-PEG (methoxy group), clone RM105 is an antibody against PEG (methoxy group) for use in WB, IH, ELISA.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Epitope Tags Gene Symbol: N/A
MABS1214
100 µL  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
AWB, IHC, ELISARbAffinity PurifiedMonoclonal Antibody
Description
Catalogue NumberMABS1214
DescriptionAnti-PEG (methoxy group) Antibody, clone RM105
Alternate Names
  • PEG
  • pegylation
  • methoxy group
  • Polyethylene glycol
  • polyethylene oxide
  • PEO
  • polyoxyethylene
  • POE
Background InformationPolyethylene glycol (PEG) is a polyether compound with many applications from industrial manufacturing to medicine. PEG is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight. PEG is a family of long chain polymers attached to a glycerine backbone. Some of the properties of PEG are nonionic, nontoxic, biocompatible, strongly hydrophilic polymer, which has a large exclusion volume in aqueous solution. PEGylation is the act of covalently coupling a PEG structure to another larger molecule, for example, a therapeutic protein, which is then referred to as a PEGylated protein. The covalent attachment of PEG (PEGylation) is commonly used to modify a variety of proteins and drugs. Some of the therapeutical benefits of PEGylated molecules include increased bioavailability, increased blood circulation of the drug, optimized pharmacokinetics, decreased immunogenicity, and decreased frequency of administration. Additional benefits of PEGylated molecules include decelerated renal excretion, improved stability towards proteolysis, increased solubility of the biopharmaceutical in aqueous solutions, increased hydrodynamic radius, reduced immunogenicity and proteolytic cleavage. This antibody reacts to the terminal methoxy group of Polyethylene glycol.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit monoclonal IgG in PBS buffer containing 1% BSA and 0.09% sodium azide
Quality LevelMQ100
Applications
ApplicationAnti-PEG (methoxy group), clone RM105 is an antibody against PEG (methoxy group) for use in WB, IH, ELISA.
Key Applications
  • Western Blotting
  • Immunohistochemistry
  • ELISA
Application NotesImmunohistochemistry Analysis: 0.5 μg/mL of this antibody detected PEG (methoxy)-BSA in injected mouse liver and kidney
ELISA Analysis: Multiple concentrations of this antibody was used to detect three different BSA-PEG conjugates (5K, 40K and 40K branched)
Biological Information
Immunogenrecombinant protein corresponding to All PEG (methoxy group).
CloneRM105
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
IsotypeIgG
Species Reactivity
  • All
Antibody TypeMonoclonal Antibody
Gene Symbol
  • N/A
Purification MethodProtein A Purfied
Molecular WeightBSA is 66 kD, methoxyPEG is 5 kD. Additional bands above 66 kD is due to different levels of conjugation and dimerization.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting on recombinant methoxyPEG conjugated BSA

Western Blotting Analysis: A 1:1;000 dilution of this antibody detected PEG (methoxy group) on conjugated recombinant BSA
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABS1214 04055977115857

Documentation

Anti-PEG (methoxy group) Antibody, clone RM105 SDS

Title

Safety Data Sheet (SDS) 

Anti-PEG (methoxy group) Antibody, clone RM105 Certificates of Analysis

TitleLot Number
Anti-PEG (methoxy group), clone RM105 QVP1406132
Anti-PEG (methoxy group), clone RM105 - VP1903220 VP1903220
Anti-PEG (methoxy group), clone RM105 - VP1908300 VP1908300
Anti-PEG (methoxy group), clone RM105 - VP2207134 VP2207134
Anti-PEG (methoxy group), clone RM105 - VP2307210 VP2307210
Anti-PEG (methoxy group), clone RM105 - VP2309280 VP2309280
Anti-PEG (methoxy group), clone RM105 - VP2311291 VP2311291
Anti-PEG (methoxy group), clone RM105 - VP2403071 VP2403071
Anti-PEG (methoxy group), clone RM105 - VP2405021 VP2405021
Anti-PEG (methoxy group), clone RM105 - VP2407245 VP2407245
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