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ABN466 Anti-NANOS2 Antibody

Detect Nanos homolog 2 using this rabbit polyclonal antibody, Anti-NANOS2 Antibody validated for use in western blotting, IHC & Immunofluorescence.

Anti-NANOS2 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: NANOS2, NOS2, Nanos2 UniProt Number: P60321
ABN466
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, RWB, IHC, IFRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABN466
DescriptionAnti-NANOS2 Antibody
Alternate Names
  • Nanos homolog 2
  • NOS-2
  • NANOS2
Background InformationNanos homolog 2 (NANOS2) is a zinc-finger containing, RNA-binding protein belonging to the nanos family. NANOS2 plays an important role in the sexual differentiation of germ cells by promoting the male fate but suppressing the female fate. It has been implicated in germ cell development in both invertebrates and vertebrates. Unlike NANOS1, whose expression in mice is dispensable, the NANOS2 and NANOS3 proteins are required for germ cell development. NANOS2-null primordial germ cells (PGCs) die only in the male gonads and show no defects in females, while NANOS3-null PGCs are lost during the migration stage regardless of sex.
References
Product Information
FormatAffinity Purified
Control
  • Rat brain tissue
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect Nanos homolog 2 using this rabbit polyclonal antibody, Anti-NANOS2 Antibody validated for use in western blotting, IHC & Immunofluorescence.
Key Applications
  • Western Blotting
  • Immunohistochemistry
  • Immunofluorescence
Application NotesImmunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected NANOS2 in human brain tissue.

Immunofluorescence Analysis: 20 µg/mL from a representative lot detected NANOS2 in human testis cells.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the N-terminus of human NANOS2.
EpitopeN-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes the N-terminus of NANOS2.
Species Reactivity
  • Human
  • Rat
Antibody TypePolyclonal Antibody
Gene Symbol
  • NANOS2
  • NOS2
  • Nanos2
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~15 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in rat brain tissue.

Western Blotting Analysis: 2 µg/mL of this antibody detected NANOS2 in 15 µg of rat brain tissue.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABN466 04053252870484