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407299
Sigma-AldrichAnti-β-Interferon Rabbit pAb
This Anti-β-Interferon Rabbit pAb is validated for use in Neutralization Studies for the detection of β-Interferon.
More>>This Anti-β-Interferon Rabbit pAb is validated for use in Neutralization Studies for the detection of β-Interferon. Less<<
Anti-β-Interferon Rabbit pAb MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Neutralization
Familletti, P.C., et al. 1981. Methods Enzymol.78, 387.
Rubinstein, S., et al. 1981. J. Virol. 37, 755.
Key Applications
Neutralization Studies
Application Notes
Neutralization Studies (see application references)
Application Comments
Does not recognize α-interferon or γ-interferon by immunoblotting. Effectively neutralizes human β-interferon (see application references). One neutralization unit is the amount of diluted serum required to neutralize 1 unit of human interferon-β. One KU = 1,000 neutralization units. Variables associated with assay conditions will dictate the proper working dilution.
Biological Information
Biological activity
≥1 x 10⁵ neutralization units/ml
Immunogen
recombinant, human β-interferon
Immunogen
Human
Host
Rabbit
Isotype
IgG
Species Reactivity
Human
Antibody Type
Polyclonal Antibody
Storage and Shipping Information
Ship Code
Dry Ice Only
Toxicity
Standard Handling
Storage
-20°C
Avoid freeze/thaw
Avoid freeze/thaw
Do not freeze
Ok to freeze
Special Instructions
Following initial thaw, aliquot and freeze (-20°C).
Anti-β-Interferon Rabbit pAb Certificates of Analysis
Title
Lot Number
407299
References
Reference overview
Familletti, P.C., et al. 1981. Methods Enzymol.78, 387. Rubinstein, S., et al. 1981. J. Virol. 37, 755.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
09-July-2007 RFH
Synonyms
Anti-IFN-β
Application
Neutralization Studies (see application references)
Description
Rabbit polyclonal antibody supplied as diluted serum. Recognizes the ~20 kDa β-interferon protein.
Host
Rabbit
Immunogen species
Human
Immunogen
recombinant, human β-interferon
Isotype
IgG
Species
human
Form
Liquid
Formulation
Serum diluted in PBS.
Biological activity
≥1 x 10⁵ neutralization units/ml
Preservative
None
Comments
Does not recognize α-interferon or γ-interferon by immunoblotting. Effectively neutralizes human β-interferon (see application references). One neutralization unit is the amount of diluted serum required to neutralize 1 unit of human interferon-β. One KU = 1,000 neutralization units. Variables associated with assay conditions will dictate the proper working dilution.
Storage
Avoid freeze/thaw -20°C
Do Not Freeze
Ok to freeze
Special Instructions
Following initial thaw, aliquot and freeze (-20°C).
Toxicity
Standard Handling
References
Familletti, P.C., et al. 1981. Methods Enzymol.78, 387. Rubinstein, S., et al. 1981. J. Virol. 37, 755.
Application references
Neutralization
Familletti, P.C., et al. 1981. Methods Enzymol.78, 387.
Rubinstein, S., et al. 1981. J. Virol. 37, 755.
