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MABS485 Anti-Ido1, clone 8G11 Antibody

Anti-Ido1, clone 8G11 Antibody is an antibody against Ido1 for use in Western Blotting, Flow Cytometry.

Anti-Ido1, clone 8G11 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Signaling Neuroscience Gene Symbol: IDO1, IDO, INDO
UniProt Number: P14902
MABS485
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
MWB, FCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABS485
DescriptionAnti-Ido1, clone 8G11 Antibody
Alternate Names
  • Ido1
  • Indoleamine 2,3-dioxygenase 1
  • IDO-1
  • Indoleamine-pyrrole 2,3-dioxygenase
Background InformationIndoleamine 2,3-dioxygenase (IDO) is an enzyme that is responsible for converting tryptophan to kynurenines. IDO is expressed by a wide variety of tissues and can be upregulated by interferon gamma. IDO modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response. IDO may be involved in the suppression of the immune response to tumours and blocking the IDO pathway may be a potential target for immunotherapy.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Ido1, clone 8G11 Antibody is an antibody against Ido1 for use in Western Blotting, Flow Cytometry.
Key Applications
  • Western Blotting
  • Flow Cytometry
Application NotesWestern Blotting Analysis: A representative lot detected Ido1 in splenic dendric cells from WT or KO mouse tissue lysate (Oberdan Leo, Universite Libre de Bruxelles).
Flow Cytometry Analysis: A representative lot detected Ido1 in splenic dendric cells from mouse (Oberdan Leo, Universite Libre de Bruxelles).
Biological Information
ImmunogenRecombinant protein corresponding to mouse Ido1.
Clone8G11
ConcentrationPlease refer to lot specific datasheet.
HostMouse
SpecificityThis antibody does not cross react with Ido2.
IsotypeIgG2aκ
Species Reactivity
  • Mouse
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • IDO1
  • IDO
  • INDO
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~44 kDa observed. Uncharacterized band(s) may appear in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in Ido1-Flag tag transfected HEK293T cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Ido1 in 10 µg of Ido1-Flag tag transfected HEK293T cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABS485 04055977136869

Documentation

Anti-Ido1, clone 8G11 Antibody SDS

Title

Safety Data Sheet (SDS) 

Anti-Ido1, clone 8G11 Antibody Certificates of Analysis

TitleLot Number
Anti-Ido1, clone 8G11 - 3193866 3193866
Anti-Ido1, clone 8G11 - 3389912 3389912
Anti-Ido1, clone 8G11 - 3728241 3728241
Anti-Ido1, clone 8G11 - 3839054 3839054
Anti-Ido1, clone 8G11 - 4034285 4034285
Anti-Ido1, clone 8G11 - 4201251 4201251
Anti-Ido1, clone 8G11 -2817484 2817484
Anti-Ido1, clone 8G11 -Q2556989 Q2556989
Anti-Ido1, clone 8G11 Monoclonal Antibody 2930086

Technical Info

Title
White Paper: Further considerations of antibody validation and usage.