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371754 Anti-Gqα- and G₁₁α-Subunits, Internal (283-300) Rabbit pAb

Anti-Gqα- and G₁₁α-Subunits, Internal (283-300), rabbit polyclonal, recognizes the ~42 kDa Gqα- and the ~43 kDa G₁₁α-subunits. Validated for use in WB and neutralization studies.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
371754
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Overview

Replacement Information

Key Spec Table

Species ReactivityHostAntibody Type
H, M, RRbPolyclonal Antibody

Products

Catalogue NumberPackaging Qty/Pack
371754-50UL Plastic ampoule 50 ul
Description
OverviewRecognizes the ~42 kDa Gqα- and the ~43 kDa G11α-subunits. Does not cross-react with other G-proteins of the non-pertussis toxin-sensitive family.
Catalogue Number371754
Brand Family Calbiochem®
References
ReferencesWange, R.L., et al. 1991. J. Biol. Chem. 266, 11409.
Pang, I-H., and Sternweis, P.C. 1990. J. Biol. Chem. 265, 18707.
Strathmann, M., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 7407.
Product Information
FormLiquid
FormulationIn 140 mM NaCl, 100 mM potassium phosphate, pH 7.0.
PreservativeNone
Quality LevelMQ100
Applications
Key Applications Immunoblotting (Western Blotting)
Neutralization Studies
Application NotesImmunoblotting (1:1000)
Neutralization Studies (see comments)
Application CommentsThe antibody recognizes both Gqα and G11α since they both share the internal sequence represented by the immunizing peptide. The antibody may also be useful to block receptor G protein coupling. Does not cross-react with other G proteins of the non-pertussis toxin sensitive family. Variables associated with assay conditions will dictate the proper working dilution.
Biological Information
Immunogena synthetic peptide (IMYSHLVDYFPEYDGPQR) corresponding to an internal amino acid sequence shared by human, mouse, and rat Gqα- and G₁₁α-subunits
HostRabbit
IsotypeIgG
Species Reactivity
  • Human
  • Mouse
  • Rat
Antibody TypePolyclonal Antibody
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
371754-50UL 04055977213355

Documentation

Anti-Gqα- and G₁₁α-Subunits, Internal (283-300) Rabbit pAb SDS

Title

Safety Data Sheet (SDS) 

Anti-Gqα- and G₁₁α-Subunits, Internal (283-300) Rabbit pAb Certificates of Analysis

TitleLot Number
371754

References

Reference overview
Wange, R.L., et al. 1991. J. Biol. Chem. 266, 11409.
Pang, I-H., and Sternweis, P.C. 1990. J. Biol. Chem. 265, 18707.
Strathmann, M., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 7407.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision02-August-2007 RFH
ApplicationImmunoblotting (1:1000)
Neutralization Studies (see comments)
DescriptionProtein A purified rabbit polyclonal antibody. Recognizes the ~42 kDa Gqα- and the ~43 kDa G11α-subunit proteins.
HostRabbit
Immunogena synthetic peptide (IMYSHLVDYFPEYDGPQR) corresponding to an internal amino acid sequence shared by human, mouse, and rat Gqα- and G₁₁α-subunits
IsotypeIgG
Specieshuman, mouse, rat
FormLiquid
FormulationIn 140 mM NaCl, 100 mM potassium phosphate, pH 7.0.
PreservativeNone
CommentsThe antibody recognizes both Gqα and G11α since they both share the internal sequence represented by the immunizing peptide. The antibody may also be useful to block receptor G protein coupling. Does not cross-react with other G proteins of the non-pertussis toxin sensitive family. Variables associated with assay conditions will dictate the proper working dilution.
Storage Avoid freeze/thaw
≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Toxicity Standard Handling
ReferencesWange, R.L., et al. 1991. J. Biol. Chem. 266, 11409.
Pang, I-H., and Sternweis, P.C. 1990. J. Biol. Chem. 265, 18707.
Strathmann, M., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 7407.