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MABN528 Anti-Glypican-4 Antibody, clone 1C7.2

MABN528
100 µL  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MWBMCulture SupernatantMonoclonal Antibody
Description
Catalogue NumberMABN528
DescriptionAnti-Glypican-4 Antibody, clone 1C7.2
Alternate Names
  • Glypican-4
  • K-glypican
  • Secreted glypican-4
Background InformationGlypican-4 is a glycosylphosphatidylinositol (GPI)-anchored cell surface heparan sulfate proteoglycan (HSPG) that is encoded by the GPC4 gene in human. Glypican-4 belongs to the family of glypican-related integral membrane proteoglycans (GRIPs) that may be involved in the control of cell division and growth regulation. Deletion of the entire GPC4 gene and the two exons at the 3' end of the adjacent GPC3 gene has been reported in a patient diagnosed with Simpson-Golabi-Behmel syndrome (SGBS).
References
Product Information
FormatCulture Supernatant
PresentationMouse monoclonal IgG2bκ in tissue culture supernatant containing 0.05% sodium azide
Quality LevelMQ100
Applications
ApplicationAnti-Glypican-4 Antibody, clone 1C7.2 is an antibody against Glypican-4 for use in Western Blotting.
Key Applications
  • Western Blotting
Application NotesWestern Blotting Analysis: A 1:500 dilution from a representative lot detected Glypican-4 in 10 µg of mouse whole embryo, mouse E16 brain, and human kidney tissue lysate.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human Glypican-4.
Clone1C7.2
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG2bκ
Species Reactivity
  • Human
  • Mouse
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • GPC4
Purification MethodUnpurified
UniProt Number
Molecular Weight~62 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in mouse E17 spinal cord tissue lysate.

Western Blotting Analysis: A 1:500 dilution of this antibody detected Glypican-4 in 10 µg of mouse E17 spinal cord tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABN528 04055977136821