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ABD77 Anti-Dax1 Antibody

This Dax1 antibody is validated for use in WB & IHC for the detection of the Dax1 protein.

Anti-Dax1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Stem Cell Research Research Sub-Category: Pluripotent & Early Differentiation Gene Symbol: NR0B1, DAX1, AHC UniProt Number: P51843
ABD77
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, RWB, IH(P)RbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABD77
Replaces04-445
DescriptionAnti-Dax1 Antibody
Alternate Names
  • Nuclear receptor subfamily 0 group B member 1
  • DSS-AHC critical region on the X chromosome protein 1
  • Nuclear receptor DAX-1
  • AHC
Background InformationDax-1 is an orphan nuclear receptor and is required for the normal development of the hypothalamic-pituitary-adrenal-gonadal axis formation. Defects in Dax-1 are the cause of X-linked adrenal hypoplasia congenital (XL-AHC); also known as X-linked Addison disease (AHX). Dax-1 also has a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency by acting as a negative regulator of Oct3/4 in ES cells.
References
Product Information
FormatAffinity Purified
Control
  • Dax1 overexpressing HEK293 transfected cell line
PresentationPurified rabbit polyclonal serum in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Dax1 antibody is validated for use in WB & IHC for the detection of the Dax1 protein.
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
Application NotesEvaluated by Immunohistochemistry in Human and Rat adrenal gland tissue. Immunohistochemsitry Analysis: A 1:1000 dilution of this antibody detected Dax1 in Human and Rat glioblastoma adrenal gland tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the Region of Ligand binding of Human Dax1.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Human
  • Rat
Species Reactivity NoteDemonstrated to react with Human and Rat Dax1. 75% Homologogous to Mouse Dax1
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • NR0B1
  • DAX1
  • AHC
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~53 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in a Dax1 overexpressing HEK293 transfected cell line. Western Blot Analysis: A 1:2000 dilution of this antibody detected Dax1 in a Dax1 overexpressing HEK293 transfected cell line.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABD77 04053252847660