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MABT198 Anti-Connexin-26 Antibody, clone 3B12.1

Anti-Connexin-26 Antibody, clone 3B12.1 is a highly specific mouse monoclonal antibody, that targets CX26 & has been tested in western blotting & IHC.

Anti-Connexin-26 Antibody, clone 3B12.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: Adhesion (CAMs) Gene Symbol: GJB2 UniProt Number: P29033
MABT198
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
R, HWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABT198
DescriptionAnti-Connexin-26 Antibody, clone 3B12.1
Alternate Names
  • Gap junction beta-2 protein
  • Connexin-26
  • Cx26
Background InformationConnexin-2 is also known as Connexin Gap junction beta-2 protein (GJB2) and Connexin-26 (Cx26). The connexins are transmembrane channels that diffuse low MW materials from one cell to a neighboring cell. Aberrant connexin-2 can cause deafness autosomal recessive type 1A (DFNB1A), deafness autosomal dominant type 3A (DFNA3A), Vohwinkel syndrome (VS), palmoplantar keratoderma with deafness (PPKDFN), keratitis-ichthyosis-deafness syndrome (KID syndrome), Bart-Pumphrey syndrome (BPS), and ichthyosis hystrix-like with deafness syndrome (HID syndrome).
References
Product Information
FormatPurified
Control
  • Rat liver tissue lysate
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Connexin-26 Antibody, clone 3B12.1 is a highly specific mouse monoclonal antibody, that targets CX26 & has been tested in western blotting & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:4,000-8,000 dilution from a representative lot detected Connexin-26 in human colon and human liver tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human Connexin-26.
Clone3B12.1
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Rat
  • Human
Species Reactivity NoteDemonstrated to react with Rat and Human. Other homologies: Mouse (92% sequence homology).
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • GJB2
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~26 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in rat liver tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Connexin-26 in 10 µg of rat liver tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABT198 04053252908750

Documentation

Anti-Connexin-26 Antibody, clone 3B12.1 SDS

Title

Safety Data Sheet (SDS) 

Anti-Connexin-26 Antibody, clone 3B12.1 Certificates of Analysis

TitleLot Number
Anti-Connexin-26, clone 3B12.1 - 3245155 3245155
Anti-Connexin-26, clone 3B12.1 - 3508393 3508393
Anti-Connexin-26, clone 3B12.1 - 3849587 3849587
Anti-Connexin-26, clone 3B12.1 - 3918587 3918587
Anti-Connexin-26, clone 3B12.1 - 4061133 4061133
Anti-Connexin-26, clone 3B12.1 - Q2192711 Q2192711
Anti-Connexin-26, clone 3B12.1 Monoclonal Antibody 3030536
Anti-Connexin-26, clone 3B12.1 Monoclonal Antibody 2924591
Anti-Connexin-26, clone 3B12.1 Monoclonal Antibody 2892880