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171375 Amphotericin B, Streptomyces sp. - CAS 1397-89-3 - Calbiochem

A polyene antifungal antibiotic that non-specifically induces loss of low molecular weight substances from cells. Binds to sterols and disrupts osmotic integrity of fungal membrane. Causes suppression

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MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Fungizone

171375
  
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Overview

Key Spec Table

CAS #Empirical Formula
1397-89-3C₄₇H₇₃NO₁₇
Description
OverviewA polyene antifungal antibiotic that non-specifically induces loss of low molecular weight substances from cells. Binds to sterols and disrupts osmotic integrity of fungal membrane. Causes suppression of bone marrow progenitor cells.
Catalogue Number171375
Brand Family Calbiochem®
SynonymsFungizone
References
ReferencesTollemar, J., et al. 1995. Transplantation 59, 45.
Charak, B.S., et al. 1994. Br. J. Haematol. 88, 693.
Barth, C., et al. 1993. J. Biophys. 64, 92.
Product Information
CAS number1397-89-3
FormYellow solid
Hill FormulaC₄₇H₇₃NO₁₇
Chemical formulaC₄₇H₇₃NO₁₇
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Purity>86% by HPLC
Safety Information according to GHS
RTECSBU2625000
Safety Information
R PhraseR: 20/21-36/37/38

Harmful by inhalation and in contact with skin.
Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C. Solutions in tissue culture media are stable for 3 days at 37°C.
Global Trade Item Number
Catalogue Number GTIN
171375 0