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116860 Adenosine Deaminase Inhibitor, DCF - CAS 53910-25-1 - Calbiochem

116860
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Overview

Key Spec Table

CAS #Empirical Formula
53910-25-1C₁₁H₁₆N₄O₄

Products

Catalogue NumberPackaging Qty/Pack
116860-10MG Glass bottle 10 mg
Description
OverviewA cell-permeable purine nucleoside compound that acts as a highly potent, tight binding transition state analog inhibitor of adenosine deaminase (ADA; Ki= 2.5 pM against partially purified human erythrocytes, and 0.48 to 9.1 nM against rat liver, rat intestine, rat hepatoma and human B cells). Reported to be an immunomodulator and exert selective toxicity towards lymphocytes.
Catalogue Number116860
Brand Family Calbiochem®
SynonymsPentostatin, S. antibioticus, 2ʹ-Deoxycoformycin, (8R)-3-(2-deoxy-β-D-erythro- pentofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol
References
ReferencesRobak, T. 2007. Cancer Treat. Rev. 33, 710.
Klohs, W.D. and Kraker, A.J., 1992. Pharmacol. Rev. 44, 459.
Agarwal, R.P., et al. 1977. Biochem. Pharmacol. 26, 359.
Product Information
CAS number53910-25-1
FormWhite solid
Hill FormulaC₁₁H₁₆N₄O₄
Chemical formulaC₁₁H₁₆N₄O₄
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Purity≥98% by HPLC
Safety Information
R PhraseR: 62-63

Possible risk of impaired fertility.
Possible risk of harm to the unborn child.
S PhraseS: 36/37/39-45

Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Harmful & Carcinogenic / Teratogenic
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Catalogue Number GTIN
116860-10MG 04055977223934