Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

116833 Adenosine 3ʹ,5ʹ-cyclic Monophosphate, 8-(4-Chlorophenylthio)-2ʹ-O-Methyl-, Sodium Salt - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 8-CPT-2ʹ-O-Me-cAMP, Na

116833
  
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Empirical Formula
C₁₇H₁₆ClN₅O₆PS • Na
Description
Overview

This product has been discontinued.



A potent, cell-permeable, and specific activator of the exchange protein activated by cyclic AMP (EPAC) [also called cAMP-guanine nucleotide-exchange factors (cAMP-GEF)] in vitro and in vivo. Does not have any effect on protein kinase A (PKA). A useful tool to discriminate between EPAC and PKA.
Note: 5 µmol = 2.54 mg.
Catalogue Number116833
Brand Family Calbiochem®
Synonyms8-CPT-2ʹ-O-Me-cAMP, Na
References
ReferencesKang, G., et al. 2003. J. Biol. Chem. 278, 8279.
Enserink, J.M., et al. 2002. Nat. Cell Biol., 4, 901.
Product Information
DeclarationSold under license of European Patent Application 02/077,219.0.
FormLyophilized
Hill FormulaC₁₇H₁₆ClN₅O₆PS • Na
Chemical formulaC₁₇H₁₆ClN₅O₆PS • Na
Hygroscopic Hygroscopic
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
116833 0

Documentation

Adenosine 3ʹ,5ʹ-cyclic Monophosphate, 8-(4-Chlorophenylthio)-2ʹ-O-Methyl-, Sodium Salt - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Adenosine 3ʹ,5ʹ-cyclic Monophosphate, 8-(4-Chlorophenylthio)-2ʹ-O-Methyl-, Sodium Salt - Calbiochem Certificates of Analysis

TitleLot Number
116833

References

Reference overview
Kang, G., et al. 2003. J. Biol. Chem. 278, 8279.
Enserink, J.M., et al. 2002. Nat. Cell Biol., 4, 901.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision22-June-2013
Synonyms8-CPT-2ʹ-O-Me-cAMP, Na
DescriptionA potent, cell-permeable, and specific activator of the exchange protein activated by cyclic AMP (EPAC) (also called cAMP-guanine nucleotide-exchange factors or cAMP-GEF) in vitro and in vivo. Does not have any effect on protein kinase A (PKA). A useful tool to discriminate between EPAC and PKA. 5 µmol = 2.54 mg. λmax = 282 nm.
FormLyophilized
Chemical formulaC₁₇H₁₆ClN₅O₆PS • Na
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityH₂O (10 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesKang, G., et al. 2003. J. Biol. Chem. 278, 8279.
Enserink, J.M., et al. 2002. Nat. Cell Biol., 4, 901.