Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

539154 20S Proteasome, Rabbit

20S Proteasome is a catalytic core enzyme of the 26S proteasome that degrades ubiquitinated proteins. Fully functional with Z-LLVY-AMC as the substrate.

20S Proteasome, Rabbit MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
539154
  
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Overview

This product has been discontinued.



Native, rabbit 20S proteasome. Catalytic core enzyme of the 26S proteasome that degrades ubiquitinated proteins. Hydrolyzes various peptide substrates and proteins with broad specificity in a non-ATP-dependent process. Can be activated by PA28 (Cat. No. 506280) or SDS.
Catalogue Number539154
Brand Family Calbiochem®
References
ReferencesStein, R.L., et al. 1996. Biochemistry 35, 3899.
Ciechanover, A. 1994. Cell 79, 13.
Dick, L.R., et al. 1994. J. Immunol. 152, 3884.
Dick, L.R., et al. 1991. Biochemistry 30, 2725.
Hough, R., et al. 1987. J. Biol. Chem. 262, 8303.
Product Information
FormLiquid
FormulationIn 150 mM NaCl, 50 mM HEPES, 1 mM DTT, pH 7.6.
Quality LevelMQ100
Applications
Biological Information
Biological activityFully functional as measured using Z-LLVY-AMC as the substrate following SDS activation
Purity≥95% by SDS-PAGE
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
539154 0

Documentation

20S Proteasome, Rabbit SDS

Title

Safety Data Sheet (SDS) 

20S Proteasome, Rabbit Certificates of Analysis

TitleLot Number
539154

References

Reference overview
Stein, R.L., et al. 1996. Biochemistry 35, 3899.
Ciechanover, A. 1994. Cell 79, 13.
Dick, L.R., et al. 1994. J. Immunol. 152, 3884.
Dick, L.R., et al. 1991. Biochemistry 30, 2725.
Hough, R., et al. 1987. J. Biol. Chem. 262, 8303.

Brochure

Title
Caspases and other Apoptosis Related Tools Brochure
Proteasomes Technical Bulletin
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision04-September-2008 RFH
DescriptionNative, rabbit 20S proteasome. Catalytic core of the 26S proteasome that degrades ubiquitinated proteins. Hydrolyzes various peptide substrates and proteins with broad specificity in a non-ATP-dependent process. Can be activated by PA28 Activator (Cat. No. 506280) or SDS.
FormLiquid
FormulationIn 150 mM NaCl, 50 mM HEPES, 1 mM DTT, pH 7.6.
Concentration Label Please refer to vial label for lot-specific concentration
Purity≥95% by SDS-PAGE
Biological activityFully functional as measured using Z-LLVY-AMC as the substrate following SDS activation
Storage Avoid freeze/thaw
≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Toxicity Standard Handling
ReferencesStein, R.L., et al. 1996. Biochemistry 35, 3899.
Ciechanover, A. 1994. Cell 79, 13.
Dick, L.R., et al. 1994. J. Immunol. 152, 3884.
Dick, L.R., et al. 1991. Biochemistry 30, 2725.
Hough, R., et al. 1987. J. Biol. Chem. 262, 8303.