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681625 W-5, Hydrochloride - CAS 61714-25-8 - Calbiochem

681625
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Tabela kluczowych gatunków

CAS #Empirical Formula
61714-25-8C₁₆H₂₂N₂O₂S · HCl

Products

Numer katalogowyOpakowanie Ilość/opak.
681625-1MG Ampulka plastikowa 1 mg
Description
OverviewA cell-permeable and reversible calmodulin antagonist that inhibits myosin light chain kinase (IC50 = 230 µM) and Ca2+-calmodulin-dependent phosphodiesterase (IC50 = 240 µM).
Catalogue Number681625
Brand Family Calbiochem®
SynonymsN-(6-Aminohexyl)-1-naphthalenesulfonamide, HCl
References
ReferencesTanaka, T., et al. 1983. Pharmacol. 26, 249.
Asano, M., et al. 1982. J. Pharmacol. Exp. Ther. 220, 191.
Hidaka, H. 1981. Prot. Nuc. Acid Enz. 26, 977.
Tanaka, T., and Hidaka, H. 1980. J. Biol. Chem. 255, 11078.
Product Information
CAS number61714-25-8
ATP CompetitiveN
FormCrystalline solid
Hill FormulaC₁₆H₂₂N₂O₂S · HCl
Chemical formulaC₁₆H₂₂N₂O₂S · HCl
Hygroscopic Hygroscopic
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary TargetMyosin light chain kinase (Mlck)
Primary Target IC<sub>50</sub>230 µM and 240 µM against myosin light chain kinase and Ca2+-calmodulin-dependent phosphodiesterase, respectively.
Purity≥98% by NMR
Physicochemical Information
Cell permeableY
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.
Global Trade Item Number
Numer katalogowy GTIN
681625-1MG 04055977260137